Dr. Richard Johnson

Exactly. And so just like currently, there are different groups that are saying, okay, they've got insulin resistance in the brain. How about if we give insulin through the nose, through the nostrils, where it can actually get to the brain directly? And can we treat the disease? Can we improve things? And there are early studies saying that might help a little bit.

Exactly. And so just like currently, there are different groups that are saying, okay, they've got insulin resistance in the brain. How about if we give insulin through the nose, through the nostrils, where it can actually get to the brain directly? And can we treat the disease? Can we improve things? And there are early studies saying that might help a little bit.

And there are people giving anti-inflammatories that can block the inflammation in the brain. They're seeing a little bit of protection. But the problem, Drew, with all these kinds of problems, of these approaches, is they're trying to patch They're trying to put out the fire, but they're not trying to figure out what's causing the fire.

And there are people giving anti-inflammatories that can block the inflammation in the brain. They're seeing a little bit of protection. But the problem, Drew, with all these kinds of problems, of these approaches, is they're trying to patch They're trying to put out the fire, but they're not trying to figure out what's causing the fire.

And there are people giving anti-inflammatories that can block the inflammation in the brain. They're seeing a little bit of protection. But the problem, Drew, with all these kinds of problems, of these approaches, is they're trying to patch They're trying to put out the fire, but they're not trying to figure out what's causing the fire.

And what's fantastic about this story that I'm going to share with you is that I'm going to try to show you how it happens and how we can prevent it. And at the end, let's talk about all the ways and the evidence that we can actually reverse or block early Alzheimer's and so forth, because it's a very exciting area.

And what's fantastic about this story that I'm going to share with you is that I'm going to try to show you how it happens and how we can prevent it. And at the end, let's talk about all the ways and the evidence that we can actually reverse or block early Alzheimer's and so forth, because it's a very exciting area.

And what's fantastic about this story that I'm going to share with you is that I'm going to try to show you how it happens and how we can prevent it. And at the end, let's talk about all the ways and the evidence that we can actually reverse or block early Alzheimer's and so forth, because it's a very exciting area.

You're absolutely right. So we have identified two mutations that have occurred in the past, both kind of interesting stories that make us more susceptible to obesity and diabetes. and at the same time may also have a role in increasing our risk for Alzheimer's. But the fundamental issue is not just those mutations, but what is this pathway that's causing obesity and diabetes?

You're absolutely right. So we have identified two mutations that have occurred in the past, both kind of interesting stories that make us more susceptible to obesity and diabetes. and at the same time may also have a role in increasing our risk for Alzheimer's. But the fundamental issue is not just those mutations, but what is this pathway that's causing obesity and diabetes?

You're absolutely right. So we have identified two mutations that have occurred in the past, both kind of interesting stories that make us more susceptible to obesity and diabetes. and at the same time may also have a role in increasing our risk for Alzheimer's. But the fundamental issue is not just those mutations, but what is this pathway that's causing obesity and diabetes?

So what I'd love to do is to take you through that part and then we can then hit the mutations and the survival pathway in the past as well.

So what I'd love to do is to take you through that part and then we can then hit the mutations and the survival pathway in the past as well.

So what I'd love to do is to take you through that part and then we can then hit the mutations and the survival pathway in the past as well.

So I was very interested in what was causing obesity and diabetes and through a series of adventures and research adventures related to doing different studies, we came to the observation that uric acid was very important in obesity and diabetes. And uric acid is a substance that circulates in our blood and it's like a breakdown product of energy. So when energy breaks down, energy is

So I was very interested in what was causing obesity and diabetes and through a series of adventures and research adventures related to doing different studies, we came to the observation that uric acid was very important in obesity and diabetes. And uric acid is a substance that circulates in our blood and it's like a breakdown product of energy. So when energy breaks down, energy is

So I was very interested in what was causing obesity and diabetes and through a series of adventures and research adventures related to doing different studies, we came to the observation that uric acid was very important in obesity and diabetes. And uric acid is a substance that circulates in our blood and it's like a breakdown product of energy. So when energy breaks down, energy is

we call energy ATP. And that's what we use to do everything we want. So the mitochondria, these energy factories, produce ATP. And the ATP is what gives us the energy. There's really two types of energy. There's the active energy, which is the ATP. That's for, you know, talking, running, jumping.

we call energy ATP. And that's what we use to do everything we want. So the mitochondria, these energy factories, produce ATP. And the ATP is what gives us the energy. There's really two types of energy. There's the active energy, which is the ATP. That's for, you know, talking, running, jumping.

we call energy ATP. And that's what we use to do everything we want. So the mitochondria, these energy factories, produce ATP. And the ATP is what gives us the energy. There's really two types of energy. There's the active energy, which is the ATP. That's for, you know, talking, running, jumping.