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Dr. Richard Moulange

πŸ‘€ Speaker
1784 total appearances

Appearances Over Time

Podcast Appearances

80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

AI did much, much better.

833.242 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

So back in early 25, when the paper was released, OpenAI's best model at the time, the O series models, O1, O3, I think it was O3, got something like 45%.

835.462 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

The best AI systems were getting double top virology experts answering in their own area of expertise about these tacit knowledge problems.

846.841 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

Why has this petri dish gone wrong?

855.315 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

Or what is going on in this experiment that doesn't make sense?

857.539 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

This is huge because this put pay to the claim that tacit knowledge barriers would always and inevitably be something that could never be overcome.

860.605 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

The eval doesn't answer everything about tacit knowledge.

870.841 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

You're quite right.

873.345 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

You talked about holding a pipette or how to sort of pour a particular kind of gel.

873.926 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

These are sort of very physical things that it's not easy to test in eval.

879.615 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

But the test really does get an awful lot of difficult knowledge that humans themselves say are huge blockers on modern state-of-the-art work.

882.88 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

And we know that are blockers because they didn't do very well.

892.615 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

And models could do much, much better.

895.9 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

Yes and no.

910.454 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

It moved certain people in the community a lot.

911.155 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

And people really woke up to, oh, we thought it would be a few years until this tacit knowledge thing really started kicking in.

914.898 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

Oh, it looks like we're here already.

921.424 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

And I'll note it's not just AI has been much better than individual experts.

923.286 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

They even went back and got teams of experts together.

927.569 View full episode β†’
80,000 Hours Podcast
AI designs genomes from scratch & outperforms virologists at lab work. What could go wrong? | Dr Richard Moulange, CLTR

And the teams still weren't as good as the best AI.

930.652 View full episode β†’