Dr. Robert Turesky

And so there are many treatments and new medicines that are coming or are on the market that also are impacting or trying to kill these cancer cells by inhibition of DNA repair or damage. And so there are people that do have a higher prostate cancer risk or aggressiveness. And so these treatments come in line, but I'd say probably, I think my, my memory is correct.

And so there are many treatments and new medicines that are coming or are on the market that also are impacting or trying to kill these cancer cells by inhibition of DNA repair or damage. And so there are people that do have a higher prostate cancer risk or aggressiveness. And so these treatments come in line, but I'd say probably, I think my, my memory is correct.

70, 80% of these cancers would not be considered aggressive and metastatic, but they're clearly a subset that is.

70, 80% of these cancers would not be considered aggressive and metastatic, but they're clearly a subset that is.

Okay. Uh, so as Clarence mentioned, uh, African-American men do have, uh, amongst the highest risk for developing prostate cancer, certainly in the United States and Northern America. And there are a number of potential reasons for this. First of all, again, prostate cancer, it's multifactorial. There are many things that contribute to the risk of disease. One is genetic.

Okay. Uh, so as Clarence mentioned, uh, African-American men do have, uh, amongst the highest risk for developing prostate cancer, certainly in the United States and Northern America. And there are a number of potential reasons for this. First of all, again, prostate cancer, it's multifactorial. There are many things that contribute to the risk of disease. One is genetic.

And so clearly there are African-Americans and whites that we have differences in our genetic makeup. It's thought that African Americans may have a higher prevalence for faulty genes that are involved in DNA repair or protective mechanisms. We're exposed to chemicals in the diet, the environment, or even in our bodies that could damage DNA. And we have different enzymes in our bodies that are

And so clearly there are African-Americans and whites that we have differences in our genetic makeup. It's thought that African Americans may have a higher prevalence for faulty genes that are involved in DNA repair or protective mechanisms. We're exposed to chemicals in the diet, the environment, or even in our bodies that could damage DNA. And we have different enzymes in our bodies that are

like policemen, they surveyed the cells, they surveyed the chromosomes and the genes, and they see an alteration of something that's not right, they repair the DNA, they repair the genes and mitigate mutations. But unfortunately, some different ethnicities have different levels of expression of these enzymes or faulty enzymes.

like policemen, they surveyed the cells, they surveyed the chromosomes and the genes, and they see an alteration of something that's not right, they repair the DNA, they repair the genes and mitigate mutations. But unfortunately, some different ethnicities have different levels of expression of these enzymes or faulty enzymes.

And so those that have faulty enzymes are at higher risk for cancer, okay? Most, many cancers are thought to be attributed to some sort of chemical exposure, or those chemicals are contributing to the risk. So I work, I study a lot of different chemicals that are produced, for instance, in tobacco smoke. Tobacco smoking causes lung cancer, okay?

And so those that have faulty enzymes are at higher risk for cancer, okay? Most, many cancers are thought to be attributed to some sort of chemical exposure, or those chemicals are contributing to the risk. So I work, I study a lot of different chemicals that are produced, for instance, in tobacco smoke. Tobacco smoking causes lung cancer, okay?

And also several other cancers, but most of the carcinogens in tobacco don't form until you combust or burn the tobacco other than some nitrosamines. And so this is not a perfect analogy, but this is how I explain it to the layperson. When you cook meat at high temperature, you're producing these nice flavors and aromas that we like, whether they be in barbecued or roasted

And also several other cancers, but most of the carcinogens in tobacco don't form until you combust or burn the tobacco other than some nitrosamines. And so this is not a perfect analogy, but this is how I explain it to the layperson. When you cook meat at high temperature, you're producing these nice flavors and aromas that we like, whether they be in barbecued or roasted

Actually, less the roasted meat, but the barbecued high temperature flames meats. You're charring the surface of the meats the same way as you kind of produce chemicals in the tobacco. We're producing these flavors and aromas that we like in the cooked meats.

Actually, less the roasted meat, but the barbecued high temperature flames meats. You're charring the surface of the meats the same way as you kind of produce chemicals in the tobacco. We're producing these flavors and aromas that we like in the cooked meats.

But unfortunately, there are a series of different compounds that are produced at high temperatures in meat that we know are cancer causing agents. at high doses, at high doses, an experimental laboratory animal, but they could be contributing to human cancers.

But unfortunately, there are a series of different compounds that are produced at high temperatures in meat that we know are cancer causing agents. at high doses, at high doses, an experimental laboratory animal, but they could be contributing to human cancers.

So African-Americans, at least based upon some of the data in the literature from behavioral scientists, have reported that African-Americans have more frequently eat well-done cooked meats, barbecued meats, than, say, do white men. So some of the chemicals that I work on in cooked meats actually cause prostate cancer in laboratory animals, rats and mice at high doses.

So African-Americans, at least based upon some of the data in the literature from behavioral scientists, have reported that African-Americans have more frequently eat well-done cooked meats, barbecued meats, than, say, do white men. So some of the chemicals that I work on in cooked meats actually cause prostate cancer in laboratory animals, rats and mice at high doses.