Dr. Rocio Salas-Whalen
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Podcast Appearances
It stimulates your pancreas to make more insulin when your sugar goes above normal. But if somebody who doesn't have diabetes and their glucose is normal, it doesn't touch the pancreas. Interesting.
Again, as with any drug we see, we have off-label uses. And what's happening is when we started somebody with type 2 diabetes on these drugs, when they were coming back to their follow-ups, not only was their glucose improved because they're great anti-diabetic drugs, but they were losing weight.
Again, as with any drug we see, we have off-label uses. And what's happening is when we started somebody with type 2 diabetes on these drugs, when they were coming back to their follow-ups, not only was their glucose improved because they're great anti-diabetic drugs, but they were losing weight.
Again, as with any drug we see, we have off-label uses. And what's happening is when we started somebody with type 2 diabetes on these drugs, when they were coming back to their follow-ups, not only was their glucose improved because they're great anti-diabetic drugs, but they were losing weight.
And to have that as a diabetes treatment, a drug that lowers your sugar and also helps with weight loss, it was unseen because most medications for diabetes promote weight gain.
And to have that as a diabetes treatment, a drug that lowers your sugar and also helps with weight loss, it was unseen because most medications for diabetes promote weight gain.
And to have that as a diabetes treatment, a drug that lowers your sugar and also helps with weight loss, it was unseen because most medications for diabetes promote weight gain.
It is fantastic, especially for type 2 diabetes, that weight gain or obesity goes hand in hand with diabetes. And before, with the medications that we had, we had to choose. Either we help with the glucose or we help with the weight. And many times we wanted to bring the glucose and that's what we had available.
It is fantastic, especially for type 2 diabetes, that weight gain or obesity goes hand in hand with diabetes. And before, with the medications that we had, we had to choose. Either we help with the glucose or we help with the weight. And many times we wanted to bring the glucose and that's what we had available.
It is fantastic, especially for type 2 diabetes, that weight gain or obesity goes hand in hand with diabetes. And before, with the medications that we had, we had to choose. Either we help with the glucose or we help with the weight. And many times we wanted to bring the glucose and that's what we had available.
They started back in 2000. So, I mean, even for 2005, for the FDA approval, they're starting in the 90s. right, with the first one. But in regards for weight loss, it started around 2005, 2006. Gotcha. And then the first one approved for weight loss was in 2012, named Saxenda, also a daily injection.
They started back in 2000. So, I mean, even for 2005, for the FDA approval, they're starting in the 90s. right, with the first one. But in regards for weight loss, it started around 2005, 2006. Gotcha. And then the first one approved for weight loss was in 2012, named Saxenda, also a daily injection.
They started back in 2000. So, I mean, even for 2005, for the FDA approval, they're starting in the 90s. right, with the first one. But in regards for weight loss, it started around 2005, 2006. Gotcha. And then the first one approved for weight loss was in 2012, named Saxenda, also a daily injection.
So we moved from the twice a day injection to the once a day injection, but it's still severe side effects where we're nausea or vomiting. And it was hard to get to higher doses where we see most of the weight loss because of the side effects. Then eventually in 2017, we have the poster child of these drugs, which is Osempek. That was when it was approved for type 2 diabetes.
So we moved from the twice a day injection to the once a day injection, but it's still severe side effects where we're nausea or vomiting. And it was hard to get to higher doses where we see most of the weight loss because of the side effects. Then eventually in 2017, we have the poster child of these drugs, which is Osempek. That was when it was approved for type 2 diabetes.
So we moved from the twice a day injection to the once a day injection, but it's still severe side effects where we're nausea or vomiting. And it was hard to get to higher doses where we see most of the weight loss because of the side effects. Then eventually in 2017, we have the poster child of these drugs, which is Osempek. That was when it was approved for type 2 diabetes.
In 2021, Osempek became also approved for weight loss independent of diabetes and then renamed it as Wegovii. Wait, what, Gove and Ozempic are the same thing? It's the same drug, yeah. When a GLP-1 gets approved initially for type 2 diabetes and then eventually gets approved separate exclusively for weight loss, they're rebranded.
In 2021, Osempek became also approved for weight loss independent of diabetes and then renamed it as Wegovii. Wait, what, Gove and Ozempic are the same thing? It's the same drug, yeah. When a GLP-1 gets approved initially for type 2 diabetes and then eventually gets approved separate exclusively for weight loss, they're rebranded.
In 2021, Osempek became also approved for weight loss independent of diabetes and then renamed it as Wegovii. Wait, what, Gove and Ozempic are the same thing? It's the same drug, yeah. When a GLP-1 gets approved initially for type 2 diabetes and then eventually gets approved separate exclusively for weight loss, they're rebranded.
They just changed the name, but it's the same drug, same pharmaceutical, same dosing.