Dr. Roger Sur

And CVAC is not the only device, but that is the device that I'm most familiar with as someone that I've used. But I'd like to talk about the other devices as well, because CVAC is not the only one. But that's really how it all started about 10 years ago. And currently that device is now available in the United States. Can I talk more about the history or?

yeah i mean from idea to a product that's ostensibly you know approved by the fda to use in humans that's not like something that happens overnight it may take a decade yeah starting in a lab using pig kidneys putting sand in the kidneys and then putting an axis sheath up there and trying to suction it back out with the single with the syringe and different catheters that was all part of the evolution which looking back i still got pictures it was

yeah i mean from idea to a product that's ostensibly you know approved by the fda to use in humans that's not like something that happens overnight it may take a decade yeah starting in a lab using pig kidneys putting sand in the kidneys and then putting an axis sheath up there and trying to suction it back out with the single with the syringe and different catheters that was all part of the evolution which looking back i still got pictures it was

yeah i mean from idea to a product that's ostensibly you know approved by the fda to use in humans that's not like something that happens overnight it may take a decade yeah starting in a lab using pig kidneys putting sand in the kidneys and then putting an axis sheath up there and trying to suction it back out with the single with the syringe and different catheters that was all part of the evolution which looking back i still got pictures it was

It was fun at that time to think, hey, maybe this will work and see now where we're at. It's really brings me a lot of joy. So what happened is a company was eventually formed and they created the first steerable vacuum aspiration system, which is CVAC 1.0. There's now a 2.0 out there. The CVAC 1.0 was good, but it was done under fluoroscopy. There was no camera associated with it.

It was fun at that time to think, hey, maybe this will work and see now where we're at. It's really brings me a lot of joy. So what happened is a company was eventually formed and they created the first steerable vacuum aspiration system, which is CVAC 1.0. There's now a 2.0 out there. The CVAC 1.0 was good, but it was done under fluoroscopy. There was no camera associated with it.

It was fun at that time to think, hey, maybe this will work and see now where we're at. It's really brings me a lot of joy. So what happened is a company was eventually formed and they created the first steerable vacuum aspiration system, which is CVAC 1.0. There's now a 2.0 out there. The CVAC 1.0 was good, but it was done under fluoroscopy. There was no camera associated with it.

And about 2,000 cases were performed throughout the United States. There was in fact even a multi-institutional randomized controlled trial called the ASPIRE trial, which was performed to demonstrate its efficacy over just ureteroscopy and basketing, which in fact it did.

And about 2,000 cases were performed throughout the United States. There was in fact even a multi-institutional randomized controlled trial called the ASPIRE trial, which was performed to demonstrate its efficacy over just ureteroscopy and basketing, which in fact it did.

And about 2,000 cases were performed throughout the United States. There was in fact even a multi-institutional randomized controlled trial called the ASPIRE trial, which was performed to demonstrate its efficacy over just ureteroscopy and basketing, which in fact it did.

But I think a lot of the critics were, you know, gave the company feedback as to, look, you know, this is great, but I can't really see what I'm doing here. And wouldn't it be nice if we could see something? So their engineers went back to the drawing board and they came out with 2.0, which is an all-in-one system that actually replaces the ureter scope because it has...

But I think a lot of the critics were, you know, gave the company feedback as to, look, you know, this is great, but I can't really see what I'm doing here. And wouldn't it be nice if we could see something? So their engineers went back to the drawing board and they came out with 2.0, which is an all-in-one system that actually replaces the ureter scope because it has...

But I think a lot of the critics were, you know, gave the company feedback as to, look, you know, this is great, but I can't really see what I'm doing here. And wouldn't it be nice if we could see something? So their engineers went back to the drawing board and they came out with 2.0, which is an all-in-one system that actually replaces the ureter scope because it has...

A camera has constant irrigation, constant aspiration, the ability to break up stones with a laser, and even collect. It has a little canister attached to the scope. So as you're breaking up the stones and aspirating, you're looking at the canister just literally filling up with stones. So that's the current generation that we're using right now for CVEC, and that's where we're at with that.

A camera has constant irrigation, constant aspiration, the ability to break up stones with a laser, and even collect. It has a little canister attached to the scope. So as you're breaking up the stones and aspirating, you're looking at the canister just literally filling up with stones. So that's the current generation that we're using right now for CVEC, and that's where we're at with that.

A camera has constant irrigation, constant aspiration, the ability to break up stones with a laser, and even collect. It has a little canister attached to the scope. So as you're breaking up the stones and aspirating, you're looking at the canister just literally filling up with stones. So that's the current generation that we're using right now for CVEC, and that's where we're at with that.

Well, Brian Eisner and I, we would go to the lab at University of California, Irvine with the team and we used a live porcine models. And so we would perform the ureteroscopy, use the CVAC, and then pass a scope back up there to see what would happen with the hopes that, please, please, please don't let there be too much mucosal injury. And fortunately, we never really saw a lot of mucosal injury.

Well, Brian Eisner and I, we would go to the lab at University of California, Irvine with the team and we used a live porcine models. And so we would perform the ureteroscopy, use the CVAC, and then pass a scope back up there to see what would happen with the hopes that, please, please, please don't let there be too much mucosal injury. And fortunately, we never really saw a lot of mucosal injury.

Well, Brian Eisner and I, we would go to the lab at University of California, Irvine with the team and we used a live porcine models. And so we would perform the ureteroscopy, use the CVAC, and then pass a scope back up there to see what would happen with the hopes that, please, please, please don't let there be too much mucosal injury. And fortunately, we never really saw a lot of mucosal injury.

And even more fortunately, it didn't translate into clinical trauma. So again, in the RCT and in our use, anecdotally, it really is a safe device, but it just was not adequate enough because we couldn't see. We're using fluoroscopy. Even though it was steerable, we couldn't see it visually.