Dr. Sagen Zac-Varghese
๐ค SpeakerAppearances Over Time
Podcast Appearances
For women, when you're about 40, you start to lose bone mass, and then that accelerates more rapidly during menopause.
For men, that happens five to ten years later, and men achieve a higher peak bone mass than women.
So you have a kind of bone age graph.
So to achieve that peak bone mass,
at 25 is really good that's a good thing to do you can think of it as money in the bank for when you're older when later as we lose bone so you lose about one percent of bone per year afterwards
Thank you for asking, Chris.
So the bone modelling is when you're growing.
So you have two groups of cells.
You have your osteoblasts and your osteoclasts.
So the remodeling is when the bone has stress going through it or there's micro cracks or damage and then the bone gets fixed.
That's your remodeling.
And that remodeling is really important.
And that happens with stress going through your bones.
So you have cells, other cells in your body.
So if I explain the osteoclast, these giant cells move across the bone, getting rid of that unhealthy old bone.
And then the osteoblasts come along and they fill in and they lay down osteoid, which is the unmineralized bone and
And that gets mineralized.