Dr. Sanjay Gupta

When you first started reporting on this, could you have predicted where we would be in 2026?

No, no.

What was it that gave you pause?

The initial sort of thinking was that if you started these drugs, you're probably gonna be on them for your whole life.

And I think there was some data a couple of years ago when we were working on a documentary that showed that a pretty significant percentage of people were stopping these medications.

And it was either because of cost, side effects, or they sort of felt like it got them to where they wanted to be.

And now they were just going to use lifestyle changes to sort of maintain.

What are you seeing?

I mean, is there a way of contextualizing how long people stay on these medications or if they do stay on them for life?

With these GLP drugs, they were originally for blood sugar, and then people noticed that they were losing significant amounts of weight.

And now there are all these other potential indications, seemingly unrelated, cardiovascular benefit, liver benefit.

Can you talk about some of those?

What else have we learned in terms of the benefits?

You know, we try and be very careful on this podcast not to be prescriptive about things, you know, or even making recommendations.

But it is interesting to hear about all the known benefits now beyond just weight loss of these things and potential benefits in the future.

Let me commingle two things which are in the news a lot lately.

One is just peptides in general.

I know.

And two is off-label use.

So first of all, GLP, the P is peptide.