Dr. Sarah Molasky
👤 PersonAppearances Over Time
Podcast Appearances
I mean, if you look at the health issues that many bulimic patients have, one of them is, you know, erosion of their esophagus, erosion of the valves that, you know, keep the acid in their stomach and not in their esophagus.
I mean, if you look at the health issues that many bulimic patients have, one of them is, you know, erosion of their esophagus, erosion of the valves that, you know, keep the acid in their stomach and not in their esophagus.
So all of that is really important to consider and a good reason why, you know, we really need to think about should this patient even be on this if they're having this level of side effect. And another thing that is much more serious that I mentioned before is gastroparesis. I'm not going to go through the whole list because we don't have time.
So all of that is really important to consider and a good reason why, you know, we really need to think about should this patient even be on this if they're having this level of side effect. And another thing that is much more serious that I mentioned before is gastroparesis. I'm not going to go through the whole list because we don't have time.
But gastroparesis is the biggest one that I wanted to talk about. And that's when the GI tract is paralyzed. So suddenly you just can't move things through your system anymore because the smooth muscle that's supposed to move things along is just like, no. I'm good. We're full. We don't have to move things right now.
But gastroparesis is the biggest one that I wanted to talk about. And that's when the GI tract is paralyzed. So suddenly you just can't move things through your system anymore because the smooth muscle that's supposed to move things along is just like, no. I'm good. We're full. We don't have to move things right now.
So it can go a little too far because slowed gastric emptying is one of the potential benefits of this medication that you feel full for longer because your stomach isn't just taking in food and then dumping it into your intestines. It's taking in food and then like slowly moving it into your intestines. But if that gets way too slow, it is horrible.
So it can go a little too far because slowed gastric emptying is one of the potential benefits of this medication that you feel full for longer because your stomach isn't just taking in food and then dumping it into your intestines. It's taking in food and then like slowly moving it into your intestines. But if that gets way too slow, it is horrible.
And like I said, there are some things with like potential pancreatic cancer risk, potential thyroid cancer risk, but that hasn't really been supported with data yet because we don't have long-term data.
And like I said, there are some things with like potential pancreatic cancer risk, potential thyroid cancer risk, but that hasn't really been supported with data yet because we don't have long-term data.
Right. Via shot, by yourself, hopefully. Yeah, right. So the two main ones I wanted to discuss when it comes to the injectables is Victoza and Ozempic, because those are the only two brands that also have specific weight loss injections. So Victoza's weight loss version is Saxenda.
Right. Via shot, by yourself, hopefully. Yeah, right. So the two main ones I wanted to discuss when it comes to the injectables is Victoza and Ozempic, because those are the only two brands that also have specific weight loss injections. So Victoza's weight loss version is Saxenda.
Same thing. And then for semaglutide, there's Ozempic and Ligovi. However, there is also an oral version of semaglutide called ribelsis, which is strictly for diabetes. And that comes in three different doses. And the complaints I've gotten from my patients on side effects have been the same as the complaints I got from them about the injections.
Same thing. And then for semaglutide, there's Ozempic and Ligovi. However, there is also an oral version of semaglutide called ribelsis, which is strictly for diabetes. And that comes in three different doses. And the complaints I've gotten from my patients on side effects have been the same as the complaints I got from them about the injections.
Um, so despite it being a daily pill, which, you know, my, my thought process was, well, if it's daily, maybe the side effects are less noticeable because it's more steady over time and you're not like doing an injection and then whatever. Uh, no, I haven't noticed a difference. I'm still noticing patients complaining about, you know, nausea, upset stomach, et cetera. Yeah.
Um, so despite it being a daily pill, which, you know, my, my thought process was, well, if it's daily, maybe the side effects are less noticeable because it's more steady over time and you're not like doing an injection and then whatever. Uh, no, I haven't noticed a difference. I'm still noticing patients complaining about, you know, nausea, upset stomach, et cetera. Yeah.
But Ozempic or Wegovy are once a week dosing, whereas Victoza and Saxenda are daily. So there's definitely a, not only does Ozempic show a higher weight loss than Victoza did, but also it's once a week. So for people who really don't like poking themselves, it's much more convenient.
But Ozempic or Wegovy are once a week dosing, whereas Victoza and Saxenda are daily. So there's definitely a, not only does Ozempic show a higher weight loss than Victoza did, but also it's once a week. So for people who really don't like poking themselves, it's much more convenient.