Dr. Scott Sherr

Your brain is not going to get stained blue. It's not like that's going to happen. This is a great sensational piece where showing blue brains, like you're taking methylene blue, your brain's going to turn blue. No, it's not going to do that.

Your brain is not going to get stained blue. It's not like that's going to happen. This is a great sensational piece where showing blue brains, like you're taking methylene blue, your brain's going to turn blue. No, it's not going to do that.

Now, if your brain is going to turn blue because of three milligrams per kilogram of IV methylene blue, it's because they were trying to save your life, okay? They failed, but they tried. And so it was a great headline, your brain's turning blue when taking methylene blue. Yes, if you're taking it at huge IV doses to save your life because you're going to die,

Now, if your brain is going to turn blue because of three milligrams per kilogram of IV methylene blue, it's because they were trying to save your life, okay? They failed, but they tried. And so it was a great headline, your brain's turning blue when taking methylene blue. Yes, if you're taking it at huge IV doses to save your life because you're going to die,

Oh, by all means, your brain's going to turn blue for a short period of time. I doubt it would have stayed blue if these people had actually lived to see the next day, all right? Because this would have come out of the system over time. But low doses of methylene blue are not turning your brain blue. It's only concentrating the mitochondria.

Oh, by all means, your brain's going to turn blue for a short period of time. I doubt it would have stayed blue if these people had actually lived to see the next day, all right? Because this would have come out of the system over time. But low doses of methylene blue are not turning your brain blue. It's only concentrating the mitochondria.

And then it's out of your system within about four to six hours. That's the half-life. So within about 18 hours, it's fully out of the system and comes out through your urine. All that blue pigment is gone, okay? So no blue brains have been harmed. in the world of transcriptions and others using methylene blue. So that's number one. Any questions on that?

And then it's out of your system within about four to six hours. That's the half-life. So within about 18 hours, it's fully out of the system and comes out through your urine. All that blue pigment is gone, okay? So no blue brains have been harmed. in the world of transcriptions and others using methylene blue. So that's number one. Any questions on that?

We've put out a lot of stuff over the last month or two with all this, but it's, it's all good. You know, like no, you know, all, all press is good press on some level, because I get to have these conversations with you, Dylan, and say, look, this is really, what's the brass tacks of the whole thing. Damn right. And so, and then you had Paul Saladino who came on to talk about how

We've put out a lot of stuff over the last month or two with all this, but it's, it's all good. You know, like no, you know, all, all press is good press on some level, because I get to have these conversations with you, Dylan, and say, look, this is really, what's the brass tacks of the whole thing. Damn right. And so, and then you had Paul Saladino who came on to talk about how

his response to all of this was, you know, methylene blue is only working because it increases serotonin. It has no effect on mitochondrial function because if you have optimized mitochondrial function, you don't need methylene blue. That's kind of his whole argument, right? And so first off, the first part is complete bullshit, you know, in the sense that methylene blue does increase serotonin.

his response to all of this was, you know, methylene blue is only working because it increases serotonin. It has no effect on mitochondrial function because if you have optimized mitochondrial function, you don't need methylene blue. That's kind of his whole argument, right? And so first off, the first part is complete bullshit, you know, in the sense that methylene blue does increase serotonin.

That is true. But the idea that the only effects that you have are because you have increased serotonin are completely out of, I don't even know where he got that from overall. So we have studies that show what methylene blue does in the mitochondria. We know what it does to compensate for mitochondrial dysfunction. We know it can help with energy. We know it can help with detox.

That is true. But the idea that the only effects that you have are because you have increased serotonin are completely out of, I don't even know where he got that from overall. So we have studies that show what methylene blue does in the mitochondria. We know what it does to compensate for mitochondrial dysfunction. We know it can help with energy. We know it can help with detox.

And so that's completely ludicrous to say that methylene blue only works because it increases serotonin. So methylene blue also not only works in the mitochondria, but also works as a monoimmune oxidase inhibitor, an MAOI, reversible one, which means that it prevents the breakdown of norepinephrine, dopamine, and serotonin.

And so that's completely ludicrous to say that methylene blue only works because it increases serotonin. So methylene blue also not only works in the mitochondria, but also works as a monoimmune oxidase inhibitor, an MAOI, reversible one, which means that it prevents the breakdown of norepinephrine, dopamine, and serotonin.

As a result of that, you will have more of those neurotransmitters around when you're taking methylene blue. And it is a reason why you have to be careful, actually, if you're on serotonergic drugs like SSRIs or SNRIs, which are like a newer class of antidepressants. If you're on medications for Parkinson's that increase dopamine, it can be an interaction there. You have to be careful.

As a result of that, you will have more of those neurotransmitters around when you're taking methylene blue. And it is a reason why you have to be careful, actually, if you're on serotonergic drugs like SSRIs or SNRIs, which are like a newer class of antidepressants. If you're on medications for Parkinson's that increase dopamine, it can be an interaction there. You have to be careful.

And if you are taking those meds, it doesn't mean you can't take low-dose methylene blue, but you should take it with the supervision of a healthcare provider, okay? So Paul's first argument there was that it was a serotonin effect that was improving people's function, but there's no way that that's actually what's happening.

And if you are taking those meds, it doesn't mean you can't take low-dose methylene blue, but you should take it with the supervision of a healthcare provider, okay? So Paul's first argument there was that it was a serotonin effect that was improving people's function, but there's no way that that's actually what's happening.