Dr. Scott Sherr

So what you can use there, for example, are things like kava and even some of the cannabinoids like CBD and CBG. These work on the GABA receptor, enhancing the binding of affinity for GABA to bind to that receptor too. But in addition, you also want to use something that's going to bind to the GABA receptor at the GABA site as well.

So what you can use there, for example, are things like kava and even some of the cannabinoids like CBD and CBG. These work on the GABA receptor, enhancing the binding of affinity for GABA to bind to that receptor too. But in addition, you also want to use something that's going to bind to the GABA receptor at the GABA site as well.

And this is called an obligate pair, which means that you do both at the same time. This is so that even if you're giving something that's safer, like kava or CBD, CBG, something called honokial, honokial from magnolia bark, these are all binding to the GABA site, the GABA receptor on separate sites. you want to also give them something that's going to replete their GABA levels at the same time.

And this is called an obligate pair, which means that you do both at the same time. This is so that even if you're giving something that's safer, like kava or CBD, CBG, something called honokial, honokial from magnolia bark, these are all binding to the GABA site, the GABA receptor on separate sites. you want to also give them something that's going to replete their GABA levels at the same time.

And this is called an obligate pair, which means that you do both at the same time. This is so that even if you're giving something that's safer, like kava or CBD, CBG, something called honokial, honokial from magnolia bark, these are all binding to the GABA site, the GABA receptor on separate sites. you want to also give them something that's going to replete their GABA levels at the same time.

So what I use is something called nicotinyl GABA, which is a vitamin B3 attached to the GABA molecule. That makes sure that the B3 gets across the blood-brain barrier no problem, and it takes GABA with it. And then as a result of that, you get mild B3, which is actually mildly activating, which is good.

So what I use is something called nicotinyl GABA, which is a vitamin B3 attached to the GABA molecule. That makes sure that the B3 gets across the blood-brain barrier no problem, and it takes GABA with it. And then as a result of that, you get mild B3, which is actually mildly activating, which is good.

So what I use is something called nicotinyl GABA, which is a vitamin B3 attached to the GABA molecule. That makes sure that the B3 gets across the blood-brain barrier no problem, and it takes GABA with it. And then as a result of that, you get mild B3, which is actually mildly activating, which is good.

in essence because the gaba itself in the brain is going to help you relax so you get this sort of calm relaxation without feeling too tired which is very nice another one that i use that binds to the gaba site of the gaba receptor as well is called agarin agarin is from a psychedelic mushroom called the amanita muscaria mushroom and what's really cool about this particular compound is it's non-psychedelic and so the amanita mushroom is well known as like in santa claus mythology it's well known in like for alice in wonderland and mario brothers

in essence because the gaba itself in the brain is going to help you relax so you get this sort of calm relaxation without feeling too tired which is very nice another one that i use that binds to the gaba site of the gaba receptor as well is called agarin agarin is from a psychedelic mushroom called the amanita muscaria mushroom and what's really cool about this particular compound is it's non-psychedelic and so the amanita mushroom is well known as like in santa claus mythology it's well known in like for alice in wonderland and mario brothers

in essence because the gaba itself in the brain is going to help you relax so you get this sort of calm relaxation without feeling too tired which is very nice another one that i use that binds to the gaba site of the gaba receptor as well is called agarin agarin is from a psychedelic mushroom called the amanita muscaria mushroom and what's really cool about this particular compound is it's non-psychedelic and so the amanita mushroom is well known as like in santa claus mythology it's well known in like for alice in wonderland and mario brothers

very famous mushroom known to be psychedelic because another ingredient in it called ibotenic acid which is actually neurotoxic But the agarine works on the GABA receptor at the site where GABA would bind. And so you put that in there at the same time as you use something like Hanakyle, which is increasing the receptor binding affinity for GABA itself so that you already have this combination.

very famous mushroom known to be psychedelic because another ingredient in it called ibotenic acid which is actually neurotoxic But the agarine works on the GABA receptor at the site where GABA would bind. And so you put that in there at the same time as you use something like Hanakyle, which is increasing the receptor binding affinity for GABA itself so that you already have this combination.

very famous mushroom known to be psychedelic because another ingredient in it called ibotenic acid which is actually neurotoxic But the agarine works on the GABA receptor at the site where GABA would bind. And so you put that in there at the same time as you use something like Hanakyle, which is increasing the receptor binding affinity for GABA itself so that you already have this combination.

And so as a result, you don't deplete GABA over time. You decrease the risk of withdrawal with tolerance, with dependence, and you can use very low doses for long periods of time and significant impact. So the key with enhancing the GABA receptor is that you're doing both. You're enhancing it by giving it something that supports on that allosteric site.

And so as a result, you don't deplete GABA over time. You decrease the risk of withdrawal with tolerance, with dependence, and you can use very low doses for long periods of time and significant impact. So the key with enhancing the GABA receptor is that you're doing both. You're enhancing it by giving it something that supports on that allosteric site.

And so as a result, you don't deplete GABA over time. You decrease the risk of withdrawal with tolerance, with dependence, and you can use very low doses for long periods of time and significant impact. So the key with enhancing the GABA receptor is that you're doing both. You're enhancing it by giving it something that supports on that allosteric site.

So it binds to the GABA receptor, not where GABA is binding, but on another site. And then you're also enhancing the GABA site because you're giving something like GABA, like nicotinyl GABA, vitamin B3 attached, or the agaric. So I give that preamble, John, because when you're looking at

So it binds to the GABA receptor, not where GABA is binding, but on another site. And then you're also enhancing the GABA site because you're giving something like GABA, like nicotinyl GABA, vitamin B3 attached, or the agaric. So I give that preamble, John, because when you're looking at

So it binds to the GABA receptor, not where GABA is binding, but on another site. And then you're also enhancing the GABA site because you're giving something like GABA, like nicotinyl GABA, vitamin B3 attached, or the agaric. So I give that preamble, John, because when you're looking at