Dr. Scott Sherr
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Podcast Appearances
And so over the last several decades, there's been a lot of interest in what's actually happening with methylene blue in the mitochondria. And why is it concentrating in there? What's happening? And so what we now know is that methylene blue at very low doses, you know, 4, 8, 16, 25 milligrams is a fantastic mitochondrial optimizer. And it has a very cool effect, which is very unusual.
And so over the last several decades, there's been a lot of interest in what's actually happening with methylene blue in the mitochondria. And why is it concentrating in there? What's happening? And so what we now know is that methylene blue at very low doses, you know, 4, 8, 16, 25 milligrams is a fantastic mitochondrial optimizer. And it has a very cool effect, which is very unusual.
And it's called the redox cycler. What that means is that it helps you make energy. It helps you make ATP, the energy currency. And it can do this even if some of the mitochondria isn't working very well.
And it's called the redox cycler. What that means is that it helps you make energy. It helps you make ATP, the energy currency. And it can do this even if some of the mitochondria isn't working very well.
Even if some of the complexes that are responsible for you being able to make energy in the mitochondria are not working as well as they're supposed to, you can still compensate for that using methylene blue. Now, on the other end of it, it's also working as an antioxidant. So it can actually pick up free radicals or oxidative stress. And so there's very few compounds out there that can do both.
Even if some of the complexes that are responsible for you being able to make energy in the mitochondria are not working as well as they're supposed to, you can still compensate for that using methylene blue. Now, on the other end of it, it's also working as an antioxidant. So it can actually pick up free radicals or oxidative stress. And so there's very few compounds out there that can do both.
They help you can not only increase the amount of energy you're making, but also help with the detoxification capacity at the same time. So these low doses are extremely potent at working in the mitochondria. There's also some effects on how well methylene blue can be carried, excuse me, how oxygen can be carried on red blood cells.
They help you can not only increase the amount of energy you're making, but also help with the detoxification capacity at the same time. So these low doses are extremely potent at working in the mitochondria. There's also some effects on how well methylene blue can be carried, excuse me, how oxygen can be carried on red blood cells.
Red blood cells, by the way, are the only cells in our body that do not have mitochondria. That's a fun fact. But the red blood cells carry oxygen, as we all know, and that methylene blue helps that become more efficient. And at the same time, methylene blue is working at the neurotransmitter level, helping improve your mood and your focus by increasing norepinephrine, serotonin, dopamine together.
Red blood cells, by the way, are the only cells in our body that do not have mitochondria. That's a fun fact. But the red blood cells carry oxygen, as we all know, and that methylene blue helps that become more efficient. And at the same time, methylene blue is working at the neurotransmitter level, helping improve your mood and your focus by increasing norepinephrine, serotonin, dopamine together.
At these low doses, it could be fantastically potent as a mitochondrial optimizer, as a mood booster, as an energy enhancer.
At these low doses, it could be fantastically potent as a mitochondrial optimizer, as a mood booster, as an energy enhancer.
And then at higher doses, around a milligram per kilogram, a little bit more, definitely a little bit higher sometimes, a little bit more, like one or two milligrams per kilogram, and sometimes a little bit lower than one milligram per kilogram, you get an anti-infective capacity to it.
And then at higher doses, around a milligram per kilogram, a little bit more, definitely a little bit higher sometimes, a little bit more, like one or two milligrams per kilogram, and sometimes a little bit lower than one milligram per kilogram, you get an anti-infective capacity to it.
So it's an antiviral, it's an antifungal, it's an antibacterial, it's used previously for urinary tract infections and other infections, but also still used that way in many countries around the world. And then even becoming more used again for malaria,
So it's an antiviral, it's an antifungal, it's an antibacterial, it's used previously for urinary tract infections and other infections, but also still used that way in many countries around the world. And then even becoming more used again for malaria,
because a lot of the drugs that we were using for it after the drugs were developed now no longer work against malaria because they're resistant to the organism or the organism is resistant to the medications.
because a lot of the drugs that we were using for it after the drugs were developed now no longer work against malaria because they're resistant to the organism or the organism is resistant to the medications.
Yeah. So if you are pregnant or breastfeeding, you shouldn't take methylene blue. If you're taking SSRIs, SNRIs, or dopaminergic drugs, drugs that increase dopamine, you have to be really careful because methylene blue is already increasing those particular neurotransmitters.
Yeah. So if you are pregnant or breastfeeding, you shouldn't take methylene blue. If you're taking SSRIs, SNRIs, or dopaminergic drugs, drugs that increase dopamine, you have to be really careful because methylene blue is already increasing those particular neurotransmitters.