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Dr. Sergiu Pașcă

👤 Speaker
1146 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Ion channels will open up

868.801 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

more when the temperature rises.

870.747 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So something about the circuits functioning differently during that.

872.69 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

But it's mostly anecdotic at this point.

876.435 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

And it's certainly, again, probably not present in all individuals with autism, also because autism is, again, not one single disease.

879.779 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So we would not expect it to be present in all.

887.21 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

I think, again, almost everything has been associated or thought to be causal.

918.352 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

But generally, demonstrating this is very, very difficult.

923.718 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So we cannot deny that perhaps improving the microbiome will improve the quality of life of some of these individuals.

927.221 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

But whether it's really causal, there's no clear evidence for it.

935.65 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Think about it.

940.215 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Just to give you another example, think about sleep.

941.076 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Many patients will report, especially the ones that are profoundly impaired, will have severe sleep disturbances.

943.698 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

I mean, 70%, 80% of them, they can have nights where they sleep very little, then do that for like a week.

952.242 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So just imagine even just improving the quality of sleep for those patients can do miracle.

958.801 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

I mean, all of us, right?

963.809 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

If we don't sleep for three, four days, our social skills, you know, we become socially impaired.

964.91 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So I think, of course, correcting a lot of these issues.

969.718 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So for instance, many patients are picky eaters.

973.424 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

You know, they don't like certain textures.

976.589 View full episode →