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Dr. Sergiu Pașcă

👤 Person
1146 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

And, you know, some discussions are just in terms of diagnosis that perhaps some of the girls are not getting diagnosed properly.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

We do know that some of them are very good at what we call like masking the symptoms or sort of like, you know, learning the skills, social skills and sort of like covering for that diagnosis.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

But what we do know for sure is...

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

is that there are differences in how the male and the female brain, especially around birth, can actually take up injury.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So think, for instance, about premature birth.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

You know, one of the best predictors for a premature baby in terms of outcomes, it's actually to be a female.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Just in general, females' preemies will do much better for whatever reasons.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

The way the nervous system is built, the resilience.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

We know that the maturation stage is also different for the male and the female.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Think about acquisition of certain milestones that happen much faster in girls.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

They generally tend to speak a few months earlier, to walk a few months earlier.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So just the nervous system.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

It's maturing at a different pace and can take injury differently.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So it could be that that is certainly the cause.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

But at the same time, and as we were talking, since autism is not one single disease, it is very hard to point out to one specific factor that is behind it.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

It's not part of the diagnostic criteria.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Interesting.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

But it is one of the features that has been observed.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Of course, it also has to do with just in general, like joint attention is one of the earlier.

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So, you know,