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Dr. Sergiu Pașcă

👤 Speaker
1146 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

How complex can a circuit like this become?

5923.389 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Is there any form of learning, of computation?

5926.673 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Of course, some people have raised the issue that perhaps there is sentience or awareness, consciousness.

5929.477 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Are they feeling pain?

5936.167 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So for instance, that has been like one critique for one of the recent work that we've done.

5937.188 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Of course, in that case, we know

5941.354 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

You know, the emotional component of pain is processed in different brain regions.

5943.237 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

We don't have those in a dish.

5947.242 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

So we know that they're not really feeling pain.

5949.345 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

We have the pathway of pain.

5950.967 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

But it also speaks to the fact that we need to be very careful about how we communicate this type of research.

5952.87 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Even just using terms that are trivializing can actually create a lot of confusion.

5959.839 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

And the classic example in our field has been to call these preparations, these organelles or assembloids, to call them mini-brains.

5964.045 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Then it may seem like as a trivial joke that it can do anything, you know, any harm.

5972.735 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

But you hear that for the first time, scientists have made mini brains in a dish, right?

5979.385 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

And what do you think?

5985.094 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

You think, oh, it must be a miniature human brain that they're keeping in a dish, right?

5985.675 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

Isolated.

5991.124 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

And of course, that's not true.

5991.625 View full episode →
Huberman Lab
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca

We have not made the entire nervous system.

5993.187 View full episode →