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Dr. Shebani Sethi

👤 Person
477 total appearances

Appearances Over Time

Podcast Appearances

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

Ozempic, Rigobi, and so forth. Manjaro, these are drugs now, quote drugs, but they're not really drugs. They're just mimicking your body's own GLP-1 at a much higher concentration. This is also known as the satiety hormone. I mean, it makes you feel full, which is why people don't eat because they take this shot and they don't feel full.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

Ozempic, Rigobi, and so forth. Manjaro, these are drugs now, quote drugs, but they're not really drugs. They're just mimicking your body's own GLP-1 at a much higher concentration. This is also known as the satiety hormone. I mean, it makes you feel full, which is why people don't eat because they take this shot and they don't feel full.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

And this is also why people lose weight because they take this shot They feel full, they don't want to eat as much, and they lose weight. This is typically secreted in the lower part of the intestine, but it basically reduces your appetite and promotes satiety. And it sends a single via the vagus nerve. So this is really important, this drug, right? It's Ozempic.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

And this is also why people lose weight because they take this shot They feel full, they don't want to eat as much, and they lose weight. This is typically secreted in the lower part of the intestine, but it basically reduces your appetite and promotes satiety. And it sends a single via the vagus nerve. So this is really important, this drug, right? It's Ozempic.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

And this is also why people lose weight because they take this shot They feel full, they don't want to eat as much, and they lose weight. This is typically secreted in the lower part of the intestine, but it basically reduces your appetite and promotes satiety. And it sends a single via the vagus nerve. So this is really important, this drug, right? It's Ozempic.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

So this is something your body makes. Also, there's other hormones that are regulated called CCK or cholecystokinin, peptide YY, really important. And other compounds called short-chain fatty acids. We're going to talk about why they're important. But these are made by your gut and suppress appetite by making you feel full by activating the vagus nerve. And these are things that you can regulate.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

So this is something your body makes. Also, there's other hormones that are regulated called CCK or cholecystokinin, peptide YY, really important. And other compounds called short-chain fatty acids. We're going to talk about why they're important. But these are made by your gut and suppress appetite by making you feel full by activating the vagus nerve. And these are things that you can regulate.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

So this is something your body makes. Also, there's other hormones that are regulated called CCK or cholecystokinin, peptide YY, really important. And other compounds called short-chain fatty acids. We're going to talk about why they're important. But these are made by your gut and suppress appetite by making you feel full by activating the vagus nerve. And these are things that you can regulate.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

Leptin is another hormone produced in fat cells and in the gut. And it's also the feel-full hormone. There's many of these redundant pathways in your body. And it exerts its effects through the vagus nerve. This network, this gut brain, this second brain or enteric nervous system is a vast network of, like I said, almost 500 million neurons. It's embedded in the lining of the GI tract.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

Leptin is another hormone produced in fat cells and in the gut. And it's also the feel-full hormone. There's many of these redundant pathways in your body. And it exerts its effects through the vagus nerve. This network, this gut brain, this second brain or enteric nervous system is a vast network of, like I said, almost 500 million neurons. It's embedded in the lining of the GI tract.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

Leptin is another hormone produced in fat cells and in the gut. And it's also the feel-full hormone. There's many of these redundant pathways in your body. And it exerts its effects through the vagus nerve. This network, this gut brain, this second brain or enteric nervous system is a vast network of, like I said, almost 500 million neurons. It's embedded in the lining of the GI tract.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

What's in them not only is nerve cells, but also hormonal cells, right? Enteroendocrine cells. And they're throughout the entire GI tract. And they're involved in sensing all sorts of signals, right? What nutrients you're taking in, taste, mechanical stimuli, fiber. They detect the microbes, what's going on in there. They help sense toxic compounds. So it's really a critical system.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

What's in them not only is nerve cells, but also hormonal cells, right? Enteroendocrine cells. And they're throughout the entire GI tract. And they're involved in sensing all sorts of signals, right? What nutrients you're taking in, taste, mechanical stimuli, fiber. They detect the microbes, what's going on in there. They help sense toxic compounds. So it's really a critical system.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

What's in them not only is nerve cells, but also hormonal cells, right? Enteroendocrine cells. And they're throughout the entire GI tract. And they're involved in sensing all sorts of signals, right? What nutrients you're taking in, taste, mechanical stimuli, fiber. They detect the microbes, what's going on in there. They help sense toxic compounds. So it's really a critical system.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

And as I mentioned, this is called the second brain. It operates independently, but also with the brain brain, right? The central nervous system by the vagus nerve, and it controls everything, right? Gut motility, right?

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

And as I mentioned, this is called the second brain. It operates independently, but also with the brain brain, right? The central nervous system by the vagus nerve, and it controls everything, right? Gut motility, right?

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

And as I mentioned, this is called the second brain. It operates independently, but also with the brain brain, right? The central nervous system by the vagus nerve, and it controls everything, right? Gut motility, right?

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

Whether you're constipated or have diarrhea, enzyme secretion, digesting your food, hormone release that regulates appetite, and then mention the full hormones or the hungry hormones like ghrelin. And it also affects blood flow that aids in digestion and absorbing nutrients. So it's super important. And the microbiome consists of about 100 trillion microbes, 5,000 different species.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

Whether you're constipated or have diarrhea, enzyme secretion, digesting your food, hormone release that regulates appetite, and then mention the full hormones or the hungry hormones like ghrelin. And it also affects blood flow that aids in digestion and absorbing nutrients. So it's super important. And the microbiome consists of about 100 trillion microbes, 5,000 different species.

The Dr. Hyman Show
The Gut-Brain Connection: Why Your Mental Health Starts in the Microbiome

Whether you're constipated or have diarrhea, enzyme secretion, digesting your food, hormone release that regulates appetite, and then mention the full hormones or the hungry hormones like ghrelin. And it also affects blood flow that aids in digestion and absorbing nutrients. So it's super important. And the microbiome consists of about 100 trillion microbes, 5,000 different species.