Dr. Shebani Sethi

In other words, these molecules produced from bacteria in the gut are absorbed and then impact your whole biology, including your brain and your mood. There's still a lot we don't know about what makes a healthy gut or a sick gut, but we know a lot. Now, your gut microbiome can produce healing metabolites that keep your gut and immune system healthy. Things like short-chain fatty acids.

We'll talk about those soon. Vitamins like B12, for example. Riboflavin made in your gut. Enzymes. Or it can produce harmful metabolites. So bad bugs produce bad stuff. Good bugs produce good stuff. And the bad metabolites from bad bugs can be things like cytokines. We've learned about from COVID, the cytokine storm. These are inflammatory messenger molecules of your immune system. Endotoxins.

We'll talk about those soon. Vitamins like B12, for example. Riboflavin made in your gut. Enzymes. Or it can produce harmful metabolites. So bad bugs produce bad stuff. Good bugs produce good stuff. And the bad metabolites from bad bugs can be things like cytokines. We've learned about from COVID, the cytokine storm. These are inflammatory messenger molecules of your immune system. Endotoxins.

We'll talk about those soon. Vitamins like B12, for example. Riboflavin made in your gut. Enzymes. Or it can produce harmful metabolites. So bad bugs produce bad stuff. Good bugs produce good stuff. And the bad metabolites from bad bugs can be things like cytokines. We've learned about from COVID, the cytokine storm. These are inflammatory messenger molecules of your immune system. Endotoxins.

literally poisons. We call these lipopolysaccharides. These are endotoxins, things that are toxic, produced by bacteria that can be absorbed across a leaky gut, cause you to be inflamed and create disease, including obesity and mental health issues and much more. So bad bugs make you inflamed and almost all issues related to mental health.

literally poisons. We call these lipopolysaccharides. These are endotoxins, things that are toxic, produced by bacteria that can be absorbed across a leaky gut, cause you to be inflamed and create disease, including obesity and mental health issues and much more. So bad bugs make you inflamed and almost all issues related to mental health.

literally poisons. We call these lipopolysaccharides. These are endotoxins, things that are toxic, produced by bacteria that can be absorbed across a leaky gut, cause you to be inflamed and create disease, including obesity and mental health issues and much more. So bad bugs make you inflamed and almost all issues related to mental health.

And it's really important to understand almost all mental health issues and brain issues, whether it's Parkinson's, Alzheimer's, autism, ADD, depression, anxiety, bipolar disease, schizophrenia are all caused by inflammation in the brain. So if we fix the inflammation, we can fix many of these things. And we'll talk about how to do that soon. Now, what is this gut mood connection?

And it's really important to understand almost all mental health issues and brain issues, whether it's Parkinson's, Alzheimer's, autism, ADD, depression, anxiety, bipolar disease, schizophrenia are all caused by inflammation in the brain. So if we fix the inflammation, we can fix many of these things. And we'll talk about how to do that soon. Now, what is this gut mood connection?

And it's really important to understand almost all mental health issues and brain issues, whether it's Parkinson's, Alzheimer's, autism, ADD, depression, anxiety, bipolar disease, schizophrenia are all caused by inflammation in the brain. So if we fix the inflammation, we can fix many of these things. And we'll talk about how to do that soon. Now, what is this gut mood connection?

We talked about, so what is the gut and what is the gut brain and the second brain and the first brain and the hormones? Okay, we talked about all that. So the gut microbiome actually influences brain health and function, and it impacts your mood, impacts your stress level.

We talked about, so what is the gut and what is the gut brain and the second brain and the first brain and the hormones? Okay, we talked about all that. So the gut microbiome actually influences brain health and function, and it impacts your mood, impacts your stress level.

We talked about, so what is the gut and what is the gut brain and the second brain and the first brain and the hormones? Okay, we talked about all that. So the gut microbiome actually influences brain health and function, and it impacts your mood, impacts your stress level.

So literally you can have stress molecules produced in your gut that are not because of something happening outside, but something happening inside. And it increases the risk of depression, mental illness via a complex network of things. nerve cells, endocrine cells, or hormone cells, immune pathways. It's the psychoneuroendocrine immune system, right? We talked about this a lot.

So literally you can have stress molecules produced in your gut that are not because of something happening outside, but something happening inside. And it increases the risk of depression, mental illness via a complex network of things. nerve cells, endocrine cells, or hormone cells, immune pathways. It's the psychoneuroendocrine immune system, right? We talked about this a lot.

So literally you can have stress molecules produced in your gut that are not because of something happening outside, but something happening inside. And it increases the risk of depression, mental illness via a complex network of things. nerve cells, endocrine cells, or hormone cells, immune pathways. It's the psychoneuroendocrine immune system, right? We talked about this a lot.

It involves all sorts of activities like the transport of neurotransmitters, tabloids, cytokines, and certain species of gut bacteria are directly involved in the production of neurotransmitters affecting both the gut and the brain. Let's talk about some of them. So dopamine, for example, is best known for its role in reward pathways, pleasure, motivation.

It involves all sorts of activities like the transport of neurotransmitters, tabloids, cytokines, and certain species of gut bacteria are directly involved in the production of neurotransmitters affecting both the gut and the brain. Let's talk about some of them. So dopamine, for example, is best known for its role in reward pathways, pleasure, motivation.

It involves all sorts of activities like the transport of neurotransmitters, tabloids, cytokines, and certain species of gut bacteria are directly involved in the production of neurotransmitters affecting both the gut and the brain. Let's talk about some of them. So dopamine, for example, is best known for its role in reward pathways, pleasure, motivation.

For example, we know about Adderall or these... ADD drugs, they all stimulate dopamine pathways. Sugar does. All the addictive compounds we like too. So does altruism, by the way. By the way, there are certain bacteria that help increase dopamine. Things like lactobacillus plantarum, bacillus subtilis, bacillus cereus, and certain strains of E. coli that are beneficial. Pretty cool.