Dr. Sheri Johnson

No midnight snacks.

In our study worldwide, we'll give people tools and support and coaching to shift to a time-restricted eating, and we'll look to see if we're making a difference in symptoms.

We can actually measure the activity of clock genes in their body.

throughout the course of a day by just swabbing their cheek and getting some clock gene kind of data.

And we'll be able to see if we're making a difference in clock gene expression and see a much more regular biological rhythm, day-night rhythm, for people as they follow the time-restricted eating.

I think when it comes to diet and bipolar disorder, we definitely need randomized controlled trials.

We need to understand mechanisms because that'll sometimes help us be even more refined about the diets.

But there's another whole piece of this, which is to test how well does it work in the hands of real life human beings?

How hard is it to pull off?

What do we need to shift to make it feasible for people?

Who's going to find it easier to kind of follow a diet?

Who's going to find it harder?

What kinds of support do we need to give them?

So I think there's a whole set of things about how acceptable it is, how feasible it is, what kind of context of support we have to give people.