Dr. Stacy Sims

without any real change in what they're doing, other than the fact that their exercise isn't working, their sleep is a little bit disrupted, and their body composition is completely changing.

without any real change in what they're doing, other than the fact that their exercise isn't working, their sleep is a little bit disrupted, and their body composition is completely changing.

And when we're looking at what's happening, we see that decrease in gut microbiome diversity, because we don't have as many sex hormones, so that impacts serotonin, that impacts vitamin production, that impacts parasympathetic drive. And we're also seeing a misstep in the way liver is reading fat and fat circulation. So we're seeing free fatty acids that are coming around.

And when we're looking at what's happening, we see that decrease in gut microbiome diversity, because we don't have as many sex hormones, so that impacts serotonin, that impacts vitamin production, that impacts parasympathetic drive. And we're also seeing a misstep in the way liver is reading fat and fat circulation. So we're seeing free fatty acids that are coming around.

And because we don't have as much estrogen, we don't have as much anti-inflammatory responses. So we can't pull as many free fatty acids into the mitochondria and the skeletal muscle to be used as fuel. So they circulate and the liver has a signal that goes, we're going to change that

And because we don't have as much estrogen, we don't have as much anti-inflammatory responses. So we can't pull as many free fatty acids into the mitochondria and the skeletal muscle to be used as fuel. So they circulate and the liver has a signal that goes, we're going to change that

free fatty acid into what we call esterified fatty acid which then gets stored as visceral fat and visceral fat is that dangerous fat that gets stored around the organs which is why women start to get like a minnow pot or develop a lot of abdominal adiposity so people will start seeing this and going i don't understand what's going on over the past six months i put on 10 pounds or or i put on four stone right what's going on my training's not working become very despondent

free fatty acid into what we call esterified fatty acid which then gets stored as visceral fat and visceral fat is that dangerous fat that gets stored around the organs which is why women start to get like a minnow pot or develop a lot of abdominal adiposity so people will start seeing this and going i don't understand what's going on over the past six months i put on 10 pounds or or i put on four stone right what's going on my training's not working become very despondent

And if they don't know they're in perimenopause, then they don't know that that's what's happening.

And if they don't know they're in perimenopause, then they don't know that that's what's happening.

Well, it's really symptomatic because we can't use blood tests. There isn't a definitive blood test to say, hey, you're a perimenopausal. You have to have a history of everything, of getting blood tests like every week. And no one does that.

Well, it's really symptomatic because we can't use blood tests. There isn't a definitive blood test to say, hey, you're a perimenopausal. You have to have a history of everything, of getting blood tests like every week. And no one does that.

So we have to go on symptomology, really using the sociocultural aspect of how a woman is experiencing life with her symptoms and really listen and say, okay, well, here are the things that are going on. And we try to instigate non-hormonal options. There's exercise, there's lifestyle. And then if all else is really going to shit, then we can look at using some menopause hormone therapy.

So we have to go on symptomology, really using the sociocultural aspect of how a woman is experiencing life with her symptoms and really listen and say, okay, well, here are the things that are going on. And we try to instigate non-hormonal options. There's exercise, there's lifestyle. And then if all else is really going to shit, then we can look at using some menopause hormone therapy.

Just like we were talking about a Zympak being a tool, so hormone therapy can also be a tool.

Just like we were talking about a Zympak being a tool, so hormone therapy can also be a tool.

It can. Yeah, it can. We see that there is a greater incidence of vasomotor symptoms or hot flashes for women who have a greater amount of body fat. We also see that if you have more lean mass, then you're going to have less of an incidence of insulin resistance. So body composition has a huge play in symptomology. And then you also have to look at what your mom went through.

It can. Yeah, it can. We see that there is a greater incidence of vasomotor symptoms or hot flashes for women who have a greater amount of body fat. We also see that if you have more lean mass, then you're going to have less of an incidence of insulin resistance. So body composition has a huge play in symptomology. And then you also have to look at what your mom went through.

Because if your mom had a really, really horrible time with lots of vasomotor symptoms and body composition change, there's a genetic link. Doesn't necessarily mean that you're going to experience the same thing, but you have a greater predisposition to having more severe symptomology.

Because if your mom had a really, really horrible time with lots of vasomotor symptoms and body composition change, there's a genetic link. Doesn't necessarily mean that you're going to experience the same thing, but you have a greater predisposition to having more severe symptomology.