Dr. Stephanie Venn-Watson
👤 PersonAppearances Over Time
Podcast Appearances
So it's kind of ironic that the one thing that we need, like we can't live without for 10 minutes, right, will kill us if we don't have oxygen, ends up being the same molecule that kills us over decades and decades.
So it's kind of ironic that the one thing that we need, like we can't live without for 10 minutes, right, will kill us if we don't have oxygen, ends up being the same molecule that kills us over decades and decades.
Exactly. So this insidious Jekyll and Hyde, insidious nature of oxygen really happens at the cell membrane level. You know, we're made out of three trillion cells and every one of our cells is surrounded by a membrane and armor. And that armor is made up of fatty acids. And there was this whole theory that came out from A.J. Holbert back in 2005 called the cell membrane age aging theory theory.
Exactly. So this insidious Jekyll and Hyde, insidious nature of oxygen really happens at the cell membrane level. You know, we're made out of three trillion cells and every one of our cells is surrounded by a membrane and armor. And that armor is made up of fatty acids. And there was this whole theory that came out from A.J. Holbert back in 2005 called the cell membrane age aging theory theory.
of aging, cell membrane pacemaker theory of aging. Think of that, right? And what he showed was that the more fragile the fatty acids in a cell membrane, the more susceptible those cells to being attacked by oxygen, resulting in this thing called lipid peroxidation or oxidative stress. And that then made a cell fragile fall apart. And that incited inflammation throughout the body
of aging, cell membrane pacemaker theory of aging. Think of that, right? And what he showed was that the more fragile the fatty acids in a cell membrane, the more susceptible those cells to being attacked by oxygen, resulting in this thing called lipid peroxidation or oxidative stress. And that then made a cell fragile fall apart. And that incited inflammation throughout the body
and resulted in shorter lifespans. This cell membrane pacemaker theory of aging explains how humans live longer than mice. It's all about how strong versus how fragile our cell membranes are.
and resulted in shorter lifespans. This cell membrane pacemaker theory of aging explains how humans live longer than mice. It's all about how strong versus how fragile our cell membranes are.
It does. And so it's just the, you know, kind of what you're going through here is it's a cycle that feeds on itself. So when we have, you know, oxygen and we have two fragile fatty acids in our cell membrane, and these are fatty acids that have double bonds. That's what the secret of C15 is that it's a sturdy fat that has no double bonds. So It is completely resistant to this oxidative stress.
It does. And so it's just the, you know, kind of what you're going through here is it's a cycle that feeds on itself. So when we have, you know, oxygen and we have two fragile fatty acids in our cell membrane, and these are fatty acids that have double bonds. That's what the secret of C15 is that it's a sturdy fat that has no double bonds. So It is completely resistant to this oxidative stress.
But if we have cell membranes with too many fragile fatty acids in it, oxygen goes in and attacks it. It makes it weak. The cell falls apart. That happens in, like you said, both the cell membrane or mitochondria, the powerhouses of our cells. That then sets up the cell for getting fragile, hence cellular fragility syndrome.
But if we have cell membranes with too many fragile fatty acids in it, oxygen goes in and attacks it. It makes it weak. The cell falls apart. That happens in, like you said, both the cell membrane or mitochondria, the powerhouses of our cells. That then sets up the cell for getting fragile, hence cellular fragility syndrome.
And that incites release of pro-inflammatory cytokines, this inflammatory response, and in fact, a whole new form of cell death called feroptosis. And it's entirely a new way our cells are dying due to this syndrome of lipid peroxidation, oxidative stress in our cell membranes.
And that incites release of pro-inflammatory cytokines, this inflammatory response, and in fact, a whole new form of cell death called feroptosis. And it's entirely a new way our cells are dying due to this syndrome of lipid peroxidation, oxidative stress in our cell membranes.
Right. So it goes really into the deep dive of if you're going to call a book the longevity nutrient, which, you know, this was actually Simon and Schuster reached out to me last summer, Dr. Drew. And they've been following the story and the science. They're getting out over 100 peer reviewed papers on C15 is this healthy saturated fat.
Right. So it goes really into the deep dive of if you're going to call a book the longevity nutrient, which, you know, this was actually Simon and Schuster reached out to me last summer, Dr. Drew. And they've been following the story and the science. They're getting out over 100 peer reviewed papers on C15 is this healthy saturated fat.
You still ask a lot of people today and most people have never heard of C50 and let alone that not all saturated fats are bad. So Simon and Schuster reached out and they said, this is a book, like this is a movement. And we really want you to be able to write this book, help support and get it out to the world.
You still ask a lot of people today and most people have never heard of C50 and let alone that not all saturated fats are bad. So Simon and Schuster reached out and they said, this is a book, like this is a movement. And we really want you to be able to write this book, help support and get it out to the world.
It's the story for sure. And so it's a, it's, it's the way they put is a really engaging way to explaining the science, but all through the story of, you know, starting with the dolphins and then just being able to trace the different investigations that were happening of, you know, in Japan and Korea, they were working on how C-15 has anti-cancer properties in Italy.
It's the story for sure. And so it's a, it's, it's the way they put is a really engaging way to explaining the science, but all through the story of, you know, starting with the dolphins and then just being able to trace the different investigations that were happening of, you know, in Japan and Korea, they were working on how C-15 has anti-cancer properties in Italy.