Dr. Stephanie Venn-Watson
๐ค SpeakerAppearances Over Time
Podcast Appearances
But getting to your point, we then were able to work with the Navy, funded by the Office of Naval Research for 10 years, to then let's take C-15, let's optimize it, and let's find a way to use it to actually reverse the aging process. Right. So that's what we did. And the whole journey there is in the book.
But getting to your point, we then were able to work with the Navy, funded by the Office of Naval Research for 10 years, to then let's take C-15, let's optimize it, and let's find a way to use it to actually reverse the aging process. Right. So that's what we did. And the whole journey there is in the book.
Yeah, that's absolutely right. And in fact, this, you know, kind of for a long time, longevity was seen as this kind of a far off world of kind of science fiction world. Health was something we all strive for. And just like you said, they are inextricably linked. To have longevity, you need to have health in the earlier stages.
Yeah, that's absolutely right. And in fact, this, you know, kind of for a long time, longevity was seen as this kind of a far off world of kind of science fiction world. Health was something we all strive for. And just like you said, they are inextricably linked. To have longevity, you need to have health in the earlier stages.
And the more targeted we can address it, the longer healthier we'll be and the longer we'll live. It makes a lot of sense, but it is actually a new thing to actually link health and longevity in this kind of extending ourselves as long as possible.
And the more targeted we can address it, the longer healthier we'll be and the longer we'll live. It makes a lot of sense, but it is actually a new thing to actually link health and longevity in this kind of extending ourselves as long as possible.
Yeah, that's exactly right. So, It's kind of an ironic thing, right? So when we talk about oxidative stress, which a lot of people know, they know that it's a bad thing and they want antioxidants. So we think things like blueberries and things that are antioxidant are good for us. But when we take the word apart and we look at it, we think like oxidative stress is oxygen.
Yeah, that's exactly right. So, It's kind of an ironic thing, right? So when we talk about oxidative stress, which a lot of people know, they know that it's a bad thing and they want antioxidants. So we think things like blueberries and things that are antioxidant are good for us. But when we take the word apart and we look at it, we think like oxidative stress is oxygen.
So it's kind of ironic that the one thing that we need, like we can't live without for 10 minutes, right, will kill us if we don't have oxygen, ends up being the same molecule that kills us over decades and decades.
So it's kind of ironic that the one thing that we need, like we can't live without for 10 minutes, right, will kill us if we don't have oxygen, ends up being the same molecule that kills us over decades and decades.
Exactly. So this insidious Jekyll and Hyde, insidious nature of oxygen really happens at the cell membrane level. You know, we're made out of three trillion cells and every one of our cells is surrounded by a membrane and armor. And that armor is made up of fatty acids. And there was this whole theory that came out from A.J. Holbert back in 2005 called the cell membrane age aging theory theory.
Exactly. So this insidious Jekyll and Hyde, insidious nature of oxygen really happens at the cell membrane level. You know, we're made out of three trillion cells and every one of our cells is surrounded by a membrane and armor. And that armor is made up of fatty acids. And there was this whole theory that came out from A.J. Holbert back in 2005 called the cell membrane age aging theory theory.
of aging, cell membrane pacemaker theory of aging. Think of that, right? And what he showed was that the more fragile the fatty acids in a cell membrane, the more susceptible those cells to being attacked by oxygen, resulting in this thing called lipid peroxidation or oxidative stress. And that then made a cell fragile fall apart. And that incited inflammation throughout the body
of aging, cell membrane pacemaker theory of aging. Think of that, right? And what he showed was that the more fragile the fatty acids in a cell membrane, the more susceptible those cells to being attacked by oxygen, resulting in this thing called lipid peroxidation or oxidative stress. And that then made a cell fragile fall apart. And that incited inflammation throughout the body
and resulted in shorter lifespans. This cell membrane pacemaker theory of aging explains how humans live longer than mice. It's all about how strong versus how fragile our cell membranes are.
and resulted in shorter lifespans. This cell membrane pacemaker theory of aging explains how humans live longer than mice. It's all about how strong versus how fragile our cell membranes are.
It does. And so it's just the, you know, kind of what you're going through here is it's a cycle that feeds on itself. So when we have, you know, oxygen and we have two fragile fatty acids in our cell membrane, and these are fatty acids that have double bonds. That's what the secret of C15 is that it's a sturdy fat that has no double bonds. So It is completely resistant to this oxidative stress.
It does. And so it's just the, you know, kind of what you're going through here is it's a cycle that feeds on itself. So when we have, you know, oxygen and we have two fragile fatty acids in our cell membrane, and these are fatty acids that have double bonds. That's what the secret of C15 is that it's a sturdy fat that has no double bonds. So It is completely resistant to this oxidative stress.
But if we have cell membranes with too many fragile fatty acids in it, oxygen goes in and attacks it. It makes it weak. The cell falls apart. That happens in, like you said, both the cell membrane or mitochondria, the powerhouses of our cells. That then sets up the cell for getting fragile, hence cellular fragility syndrome.
But if we have cell membranes with too many fragile fatty acids in it, oxygen goes in and attacks it. It makes it weak. The cell falls apart. That happens in, like you said, both the cell membrane or mitochondria, the powerhouses of our cells. That then sets up the cell for getting fragile, hence cellular fragility syndrome.