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Dr. Stephanie Venn-Watson

👤 Person
590 total appearances

Appearances Over Time

Podcast Appearances

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

Right, right. So the first important discovery that we made, and this was alongside Dr. Ed Dennis, who's a leader in fatty acids. So he was the editor-in-chief for the Journal for Lipid Research for 15 years. And when we first made the discovery of C15 association, right, because in the dolphins, this was just association with better health.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

we went to Dr. Dennis to Ed and shared our hypothesis and Ed was like, well, chances are this isn't gonna pan out because we've known about C-15 since the 1950s and chances are that stuff, no offense, that a dolphin veterinarian didn't discover something new about fatty acids. And he's like, but it's intriguing about the dolphins. So we spent the next three years

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

we went to Dr. Dennis to Ed and shared our hypothesis and Ed was like, well, chances are this isn't gonna pan out because we've known about C-15 since the 1950s and chances are that stuff, no offense, that a dolphin veterinarian didn't discover something new about fatty acids. And he's like, but it's intriguing about the dolphins. So we spent the next three years

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

we went to Dr. Dennis to Ed and shared our hypothesis and Ed was like, well, chances are this isn't gonna pan out because we've known about C-15 since the 1950s and chances are that stuff, no offense, that a dolphin veterinarian didn't discover something new about fatty acids. And he's like, but it's intriguing about the dolphins. So we spent the next three years

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

doing eight studies to show that C15 not only has direct benefits and is a beneficial saturated fat, like you shared, but that it meets these rare criteria of being an essential fatty acid, the first essential fatty acid to be discovered in over 90 years.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

doing eight studies to show that C15 not only has direct benefits and is a beneficial saturated fat, like you shared, but that it meets these rare criteria of being an essential fatty acid, the first essential fatty acid to be discovered in over 90 years.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

doing eight studies to show that C15 not only has direct benefits and is a beneficial saturated fat, like you shared, but that it meets these rare criteria of being an essential fatty acid, the first essential fatty acid to be discovered in over 90 years.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

Yeah, so what we've learned is that our bodies require a certain amount of C15 in our bodies, including in our cell membrane. It's a sturdy saturated fat. That is because it's an odd chain saturated fatty acid, has an odd number of carbons, it has anti-inflammatory properties. We'll talk about all the different mechanisms that C15 has.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

Yeah, so what we've learned is that our bodies require a certain amount of C15 in our bodies, including in our cell membrane. It's a sturdy saturated fat. That is because it's an odd chain saturated fatty acid, has an odd number of carbons, it has anti-inflammatory properties. We'll talk about all the different mechanisms that C15 has.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

Yeah, so what we've learned is that our bodies require a certain amount of C15 in our bodies, including in our cell membrane. It's a sturdy saturated fat. That is because it's an odd chain saturated fatty acid, has an odd number of carbons, it has anti-inflammatory properties. We'll talk about all the different mechanisms that C15 has.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

So it's really this Goldilocks healthy fatty acid that is essential to maintaining the stability of our cells. If we don't have enough C15 specifically, at least 0.2% of fatty acids are C15 in our cell membrane, our cells become fragile and we develop a nutritional deficiency syndrome, which we published last year in Metabolites called cellular fragility syndrome.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

So it's really this Goldilocks healthy fatty acid that is essential to maintaining the stability of our cells. If we don't have enough C15 specifically, at least 0.2% of fatty acids are C15 in our cell membrane, our cells become fragile and we develop a nutritional deficiency syndrome, which we published last year in Metabolites called cellular fragility syndrome.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

So it's really this Goldilocks healthy fatty acid that is essential to maintaining the stability of our cells. If we don't have enough C15 specifically, at least 0.2% of fatty acids are C15 in our cell membrane, our cells become fragile and we develop a nutritional deficiency syndrome, which we published last year in Metabolites called cellular fragility syndrome.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

the first deficiency syndrome to be discovered in 75 years, which leads to, you know, we can talk about this whole new form of cell death called phoroptosis. So it's been, you know, and accelerates everything.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

the first deficiency syndrome to be discovered in 75 years, which leads to, you know, we can talk about this whole new form of cell death called phoroptosis. So it's been, you know, and accelerates everything.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

the first deficiency syndrome to be discovered in 75 years, which leads to, you know, we can talk about this whole new form of cell death called phoroptosis. So it's been, you know, and accelerates everything.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

Right. So if you have fragile cells, your cells basically start falling apart, which is what happens when we age. So a lot of aging-related breakdown that we feel, our aching knees, our foggy brains, our slower metabolism, increased inflammation, all of those things come with more fragile cells, which leads to, if we nerd out a little bit, leads to lipid peroxidation.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

Right. So if you have fragile cells, your cells basically start falling apart, which is what happens when we age. So a lot of aging-related breakdown that we feel, our aching knees, our foggy brains, our slower metabolism, increased inflammation, all of those things come with more fragile cells, which leads to, if we nerd out a little bit, leads to lipid peroxidation.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

Right. So if you have fragile cells, your cells basically start falling apart, which is what happens when we age. So a lot of aging-related breakdown that we feel, our aching knees, our foggy brains, our slower metabolism, increased inflammation, all of those things come with more fragile cells, which leads to, if we nerd out a little bit, leads to lipid peroxidation.

The Dr. Hyman Show
The Unexpected Dolphin Discovery That May Hold the Key to Longevity | Dr. Stephanie Venn-Watson

There's this abnormal iron sitting inside the cell. They combine, and they cause this increase, like explosion of reactive oxygen species that take out the cell. So when that happens, our whole bodies get affected from our immunity to our metabolism. So it ends up that while this process, C15 deficiencies, can accelerate our aging and