Dr. Teo Soleymani
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Podcast Appearances
We found that that wasn't very effective and some people can be hospitalized and it can be life-threatening if psoriasis involves the entire body. It usually looks like red patches or plaques with kind of a silvery scale on the surface and starts usually elbows and knees or the scalp, but can involve pretty much the entirety of the body.
We found that that wasn't very effective and some people can be hospitalized and it can be life-threatening if psoriasis involves the entire body. It usually looks like red patches or plaques with kind of a silvery scale on the surface and starts usually elbows and knees or the scalp, but can involve pretty much the entirety of the body.
We found that that wasn't very effective and some people can be hospitalized and it can be life-threatening if psoriasis involves the entire body. It usually looks like red patches or plaques with kind of a silvery scale on the surface and starts usually elbows and knees or the scalp, but can involve pretty much the entirety of the body.
And what we found in the last 30 years with a lot of elegant studies and a lot of very, very nice basic science research is that it's actually due to overactivity of our skin's immune system. So there's overactivity of certain interleukins, which are these messengers that our immune cells produce, that makes the skin turnover faster than it should.
And what we found in the last 30 years with a lot of elegant studies and a lot of very, very nice basic science research is that it's actually due to overactivity of our skin's immune system. So there's overactivity of certain interleukins, which are these messengers that our immune cells produce, that makes the skin turnover faster than it should.
And what we found in the last 30 years with a lot of elegant studies and a lot of very, very nice basic science research is that it's actually due to overactivity of our skin's immune system. So there's overactivity of certain interleukins, which are these messengers that our immune cells produce, that makes the skin turnover faster than it should.
And this epiphany was remarkable because we found that instead of targeting the skin, we can target the immune system and we can eradicate or treat psoriasis entirely. And in the 90s and early 2000s, that targeting was very crude. It was a very umbrella approach. We suppressed the entire immune system and ran into the consequences of that.
And this epiphany was remarkable because we found that instead of targeting the skin, we can target the immune system and we can eradicate or treat psoriasis entirely. And in the 90s and early 2000s, that targeting was very crude. It was a very umbrella approach. We suppressed the entire immune system and ran into the consequences of that.
And this epiphany was remarkable because we found that instead of targeting the skin, we can target the immune system and we can eradicate or treat psoriasis entirely. And in the 90s and early 2000s, that targeting was very crude. It was a very umbrella approach. We suppressed the entire immune system and ran into the consequences of that.
So medications that we gave for that increased risk for infections and, you know, skin cancers, et cetera. Now we have amazing drugs that target one or two molecules, messenger molecules of our immune system and clear up people's psoriasis. I mean, we have drugs now you take three times a year and you could have head to toe psoriasis and be completely clear. It tends to run in families.
So medications that we gave for that increased risk for infections and, you know, skin cancers, et cetera. Now we have amazing drugs that target one or two molecules, messenger molecules of our immune system and clear up people's psoriasis. I mean, we have drugs now you take three times a year and you could have head to toe psoriasis and be completely clear. It tends to run in families.
So medications that we gave for that increased risk for infections and, you know, skin cancers, et cetera. Now we have amazing drugs that target one or two molecules, messenger molecules of our immune system and clear up people's psoriasis. I mean, we have drugs now you take three times a year and you could have head to toe psoriasis and be completely clear. It tends to run in families.
There is a very strong hereditary or genetic component to it. And it tends to be associated with arthritis, psoriatic arthritis. So psoriasis is like the quintessential skin condition that people see dermatologists and even rheumatologists for.
There is a very strong hereditary or genetic component to it. And it tends to be associated with arthritis, psoriatic arthritis. So psoriasis is like the quintessential skin condition that people see dermatologists and even rheumatologists for.
There is a very strong hereditary or genetic component to it. And it tends to be associated with arthritis, psoriatic arthritis. So psoriasis is like the quintessential skin condition that people see dermatologists and even rheumatologists for.
Yeah, I should probably backtrack. So psoriasis obviously comes in severity. There's mild disease, which majority of people have. There's moderate and severe.
Yeah, I should probably backtrack. So psoriasis obviously comes in severity. There's mild disease, which majority of people have. There's moderate and severe.
Yeah, I should probably backtrack. So psoriasis obviously comes in severity. There's mild disease, which majority of people have. There's moderate and severe.
And generally speaking, the most common things that we treat mild psoriasis with is creams and lotions, moisturizers, sometimes low-potency topical steroids or high-potency topical steroids, and then things like carotidlytics, like salicylic acid, that take that excess scale off.
And generally speaking, the most common things that we treat mild psoriasis with is creams and lotions, moisturizers, sometimes low-potency topical steroids or high-potency topical steroids, and then things like carotidlytics, like salicylic acid, that take that excess scale off.