Dr. Thaïs Aliabadi

So that insulin needs to be lowered.

That's why a lot of PCOS patients get prescribed metformin, right?

What does metformin do?

So metformin basically makes us more insulin sensitive.

It's opening these channels.

So sugar clears the blood and goes into the cells where it turns into energy.

No, high dose.

High dose, I mean, I start patients on 750 twice a day, but you have to start slow because PCOS patients, especially the ones with insulin resistance, which is 80% of them,

I start with 750 because it can cause sometimes GI symptoms like diarrhea, and it can also cause nausea.

So I start with 750 at night.

Then if they tolerate it, I add the 750 in the morning.

And for patients who...

are tolerating it and they still are not ovulating, their periods are still not regulating and they still have symptoms, I might up it to 1,000 twice a day.

But you see these patients who come in on 500 milligram of metformin once a day.

That's not going to touch these patients.

So metformin is one.

But before metformin, and I don't know if you know this, because of my passion for PCOS, I actually developed a calculator.

It's a platform called Ovi.

Women can go on it.

Obviously, I can't diagnose on any website, but I can tell them that, ask them.