Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
For any woman with family history of breast cancer, ovarian cancer, pancreatic cancer, prostate cancer, and the list goes on and on, they can ask their doctor to see if they qualify for genetic cancer testing.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
The company I use in my office I've used for, I don't know, over 10 years is Marriott.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
And the reason I use this specific company, there are a lot of companies that check for genetic cancer testing, right?
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
They check 80, 90 genes.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
I think Marriott only checks 63 genes, which is fine.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
But so not only Myriad checks you for the cancer-causing genes, they also calculate your tire cusick for you so the doctor can see it.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
But in addition to that, Myriad takes your tire cusick and also looks in the DNA for tiny little markers.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
These are not main genetic mutations.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
They're tiny little markers that individually don't have that much power.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
But some women walk around with tons of these markers and
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
And they add the Tyrecusic with these markers and they give you a risk score.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
Sometimes I have a patient whose Tyrecusic is 19%, but when you calculate their risk score, it jumps up to 34%.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
So for patients who fall into the very high risk category, north of 35%, those patients have the choice of either doing imaging every six months, alternating mammogram ultrasound with MRI, or asking their doctor for a medication called tamoxifen.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
That reduces the risk of breast cancer by 50% in the next 10 years of their life, or ask for a double mastectomy, which is exactly what I did.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
And I'm just going to end it by this.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
I was 48.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
I had no family history of breast cancer.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
85% of women who get breast cancer don't have it in their family.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
Less than 5% have a genetic mutation.
Huberman Lab
Female Hormone Health, PCOS, Endometriosis, Fertility & Breast Cancer | Dr. Thaïs Aliabadi
Most Americans who get it are just like me.