Dr. Todd LePine
speaker
114 appearances
3 recordings
1 series
first heard Dec 2024
last heard May 2025
Dr. Todd LePine’s voice in public audio — every appearance, attributed to the second.
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Appearances
There are certain times when there can be other causes, like you might have fat malabsorption that can cause low vitamin D, or you may have problems with the synthesis because of lack of skin oils, which when you get exposed to the sun, But by and large, low vitamin D levels is related to sunshine deficiency. And low vitamin D is not the problem. It's a symptom of another problem.
And the immune system is also benefited by sunshine exposure, healthy sunshine. I think you said you enjoy going to the tropics now and then, Caribbean, Hawaii, whatever. And we also feel good. This is another thing that I find fascinating is that there is a – a condition which is called sunshine addiction. You know, these people who are like suntan addicts?
Well, it turns out that our bodies actually produce endorphins when we are exposed to the sun. So there's a feedback mechanism. That's incredible. Oh, yeah, yeah. There's a compound that's called pro-opio-melanocorticotropin hormone. And what it means is that our bodies give a reward when we're in the sun. So we feel good. We make us want to get the sun. Oh, that's interesting.
That's why I love going in the sun. Exactly.
Exactly. And the interesting thing is it actually, you can get addicted to the sun. And it's like you can get addicted to food. I mean, your body needs food to survive and your body actually needs sunshine to survive. So, nature has built in these feedback mechanisms so that it encourages us to do it. That's incredible. Yeah, isn't that wild?
Well, I did a lot. I mean, I had her work with our nutritionist and got her off of her standard American diet. I treated her bacterial overgrowth. She had a significant SIBO test. So I treated that primarily with herbs. A lot of people will use antibiotics, things like Rifaximin or Xifaxim for SIBO. I actually find that I do just as well using antimicrobial herb preparations.
I supported her stomach acid using Betaine HCL. Some patients don't respond to that. They don't tolerate it as well. So sometimes I'll use things like apple cider vinegar. And then got her fatty acids up, gave her a little bit of borage oil and a combination of that. And then also just told her to get some healthy sunshine.
It doesn't necessarily mean that you need to go out and sunbathe or go to a sun tanning booth, but just getting healthy sunshine can help with down-regulating the immune system. And interestingly, you know, just off topic, but with COVID, there are some really interesting studies that giving high dose vitamin D helps with COVID infections.
And so COVID actually, or vitamin D, when it's at high enough levels, actually helps to keep the immune system in balance. It keeps it from getting over.
Exactly, exactly. It's like a hormone. And it's also, it actually acts like a steroid too. It's a cholesterol molecule moiety. And I oftentimes, if I'm coming down with a cold or a flu, I'll up my dose of vitamin D, especially in the winter. Absolutely.
The Dr. Hyman Show · Mold, Lyme, Gut Health, and the Mystery of Histamine Intolerance · 21 Apr 2025
podcast
We now believe that, and you sort of brought this up as part of the introductions, is that we now believe that food poisoning starts the whole process. So you... And eating is part of it. You know, back in the day, meaning like 40, 50 years ago, when we were in... kindergarten, we would sit in a sandbox and eat the sand. Now we eat salad out of a bag until we go to Club Med.
And for the first time in our life, we see salmonella or we go somewhere and we get traveler's diarrhea or we get food poisoning or whatever. We start to explore the world of food. But food poisoning triggers this. And we now have identified the toxin in food poisoning, the CDTB toxin.
that trips off some antibodies in the human body that then cause your nerves of the gut to fail or to be impaired. And so when the flow of the gut is slowed by this impairment, bacteria build up. And there's two bacteria that just flourish when it's a little more swampy. So I used to watch Survivor shows on TV on Discovery Channel. You've probably watched those.
And they always say- I like The Lost.
It's a little bit different. There's a little more raunchiness. With Survivor, you're just kind of trying to make it to a road somewhere. But the point was that he always, this guy on the Survivor show, would always say, if the water's not moving, don't drink it. If the water's flowing fast, drink it because it's cleaner. And the same thing with the small bowel. If the small bowel stagnates,
it becomes swampy and bacteria grow in it. And the same thing is happening in the human small intestine. And so it's a sequence. So food poisoning, the antibodies, and then you develop the bacterial buildup.
The interesting thing about contrasting IBD to IBS, so the antibody that we discovered is an autoantibody that is directly related to the pathology. So the higher that antibody is, the sicker you are. The antibodies in IBD are markers of IBD. They're not directly implicated in the pathophysiology. The antibody to vinculin that we discovered is directly related to the pathophysiology.
We can make rats have IBS just by giving them this toxin. And so that's very cool because it allows us to study new drugs and new therapies coming in.
Well, the four horsemen of the apocalypse of IBS are Campylobacter, Salmonella, Shigella, and some E. coli, food poisoning type of E. coli, pathogenic E. coli. Giardia can do it too. It turns out it has vinculin in its structure. And so maybe that's how you get the antibodies from Giardia. The viruses are less likely to precipitate IBS.
So the four horsemen, Campylobacter salmonella, Shigella, and E. coli. So that's... And it occurs about starts to occur about three months after you get sick. Patients will remember. Some don't remember. And they'll say, you know, they have a couple of days of diarrhea and they don't pay much attention to it.
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