Dr. Trisha Pasricha

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2,195 appearances 5 recordings 5 series first heard Mar 2026 last heard 8 Jul

Dr. Trisha Pasricha’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 5 in all, peaking in Apr 2026 with 2.

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Science Friday · How does the gut-brain connection work? · 8 Jul 2026 podcast

But if you look at that natural history, people who had that procedure, their risk of Parkinson's disease got slashed by almost half.

And it tells us that that link is probably real.

And we're looking into some of this in my lab today to try to figure out what are the triggers?

Why does it happen in some people?

Obviously, and probably not all though, there are some people where I think it does start in the brain.

What makes these two things different?

Yeah, I mean, I think that is the hope of our whole field, is that if you think about it in a way, it's it feels scary to hear that Parkinson's is starting in my gut and maybe this is happening well before I would even know that it's there.

But the other way of looking at that is to say, well, what an enormous opportunity we have.

This means that maybe there are years of time, maybe even longer, where there's a window before the disease reaches our brain.

And that's exactly what a lot of us in the field are trying to figure out is can we identify a biomarker

in the gut that will herald what may happen years down if we don't intervene.

And of course, what we need to do is also come up with a way to intervene.

And there's a lot of work being done on both of those fronts right now.

So it's actually, I mean, we're incredibly biased in that, but it's a really exciting area of research, I think, in all of medicine right now.

Tricia, what's your take on this?

Anything to add?

Yeah, I'm in agreement on most fronts here.

I mean, I think what we've found so fascinating in GI is, you know, a lot of people are hesitant about GLP-1s because they're worried about the GI side effects.

And GLP-1s is something that we study in my lab, too.

And we're finding more and more that there are these effects that GLP-1s have on

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