Dr. Vonda Wright

Mm-hmm.

Mm-hmm.

Big weights. Four reps, four sets.

Big weights. Four reps, four sets.

Mm-hmm.

Mm-hmm.

So it has to do with muscle is the sink for glucose. It is a key factor in preventing insulin resistance, not to mention strength, staying upright, not falling down, causing a fracture, right? So muscle is a metabolic endocrine organ.

So it has to do with muscle is the sink for glucose. It is a key factor in preventing insulin resistance, not to mention strength, staying upright, not falling down, causing a fracture, right? So muscle is a metabolic endocrine organ.

It releases, when it releases, you know, one of the things it releases is skeletal muscle contraction, biceps curls, causes the transcription of a protein called clotho. which is the longevity protein. About 30 years ago, it was described in Nature. It is the protein when muscle contracts that's transcribed. It works on every organ.

It releases, when it releases, you know, one of the things it releases is skeletal muscle contraction, biceps curls, causes the transcription of a protein called clotho. which is the longevity protein. About 30 years ago, it was described in Nature. It is the protein when muscle contracts that's transcribed. It works on every organ.

We know that it's critical for the longevity and repair of organs because mice, who are born without the ability to make clotho, die old, very young. Chronologically, they're very young mice, but they die very old mice because they have not enjoyed this protein clotho. We make clotho by the contraction of skeletal muscle.

We know that it's critical for the longevity and repair of organs because mice, who are born without the ability to make clotho, die old, very young. Chronologically, they're very young mice, but they die very old mice because they have not enjoyed this protein clotho. We make clotho by the contraction of skeletal muscle.

Here's a study I did years ago that showed that I measured clotho level circulating in the blood of older master's athletes, people 60, 70, 80, younger master's athletes, 40, and sedentary people. And what I found that the highest levels of circulating clotho, the longevity protein, were in young athletes, not surprising.

Here's a study I did years ago that showed that I measured clotho level circulating in the blood of older master's athletes, people 60, 70, 80, younger master's athletes, 40, and sedentary people. And what I found that the highest levels of circulating clotho, the longevity protein, were in young athletes, not surprising.

The second highest level of longevity protein clotho were in old master's athletes, 70, 80. The lowest level of longevity protein were in young sedentary people. So even old athletes had more circulating clotho than young sedentary people. So just the contraction of skeletal muscle can add to your longevity through this protein.

The second highest level of longevity protein clotho were in old master's athletes, 70, 80. The lowest level of longevity protein were in young sedentary people. So even old athletes had more circulating clotho than young sedentary people. So just the contraction of skeletal muscle can add to your longevity through this protein.

Another protein that's released with skeletal muscle contraction called galanin is transcribed, goes to the brain, works at a place called the nucleus coerulus, which is critical for resilience. It makes you more resilient. It helps you able to problem solve. And then You know, a very popular protein that is transcribed with skeletal muscle contraction is called irisin.

Another protein that's released with skeletal muscle contraction called galanin is transcribed, goes to the brain, works at a place called the nucleus coerulus, which is critical for resilience. It makes you more resilient. It helps you able to problem solve. And then You know, a very popular protein that is transcribed with skeletal muscle contraction is called irisin.

It's the exercise protein, which, you know, it works on bone. It works on fat to brown fat, from white fat to brown fat, which has higher thermogenesis. It has higher mitochondrial load. So muscle, just in doing its thing, not just looking pretty in a gym mirror, does all these metabolic functions. And so that's why we think It has such a key role in longevity.

It's the exercise protein, which, you know, it works on bone. It works on fat to brown fat, from white fat to brown fat, which has higher thermogenesis. It has higher mitochondrial load. So muscle, just in doing its thing, not just looking pretty in a gym mirror, does all these metabolic functions. And so that's why we think It has such a key role in longevity.