Dr. Will Bulsiewicz

And when you take this lipopolysaccharide, basically what you're recreating is what happens when a person has a damaged gut. Interesting. Because when you have a damaged gut, Those microbes, they live inside the tube of the intestine. And as we discussed at the very beginning of the show, that tube is outside of our body.

We have a single layer of cells called the gut epithelium that basically protect us. Because on the other side of the epithelial layer is 60 to 70% of our immune cells. Wow. Okay. So the immune system is there to protect us on the other side. And the single layer of cells, it's like the wall of our castle.

We have a single layer of cells called the gut epithelium that basically protect us. Because on the other side of the epithelial layer is 60 to 70% of our immune cells. Wow. Okay. So the immune system is there to protect us on the other side. And the single layer of cells, it's like the wall of our castle.

And when our gut breaks down, when our microbes are damaged, when we don't have enough anti-inflammatory short chain fatty acids, you start to see this gut barrier breakdown. We get what people may call leaky gut. And what leaks is the lipopolysaccharide. This lipopolysaccharide that they were injecting in this study, basically what they were recreating, they were not recreating an infection.

And when our gut breaks down, when our microbes are damaged, when we don't have enough anti-inflammatory short chain fatty acids, you start to see this gut barrier breakdown. We get what people may call leaky gut. And what leaks is the lipopolysaccharide. This lipopolysaccharide that they were injecting in this study, basically what they were recreating, they were not recreating an infection.

They were recreating chronic inflammation.

They were recreating chronic inflammation.

That comes from a damaged gut.

That comes from a damaged gut.

Yeah.

Yeah.

The thing about this is I think this is universally applicable and something that every single listener, unless you're on a 100% animal-based diet... Every single one of these listeners can apply this to their life. Increase the diversity of plants in your diet. Where this came from, Drew, is a study called the American Gut Project. That's where it originally started.

The thing about this is I think this is universally applicable and something that every single listener, unless you're on a 100% animal-based diet... Every single one of these listeners can apply this to their life. Increase the diversity of plants in your diet. Where this came from, Drew, is a study called the American Gut Project. That's where it originally started.

The thing about this is I think this is universally applicable and something that every single listener, unless you're on a 100% animal-based diet... Every single one of these listeners can apply this to their life. Increase the diversity of plants in your diet. Where this came from, Drew, is a study called the American Gut Project. That's where it originally started.

And the American Gut Project actually was an international study and included like 52 territories and countries across the globe, especially the United States and the U.K., And it was the first time that they had microbiome samples for over 10,000 people and simultaneously all kinds of information about their diet, their lifestyle. What were they eating? How were they eating?

And the American Gut Project actually was an international study and included like 52 territories and countries across the globe, especially the United States and the U.K., And it was the first time that they had microbiome samples for over 10,000 people and simultaneously all kinds of information about their diet, their lifestyle. What were they eating? How were they eating?

And the American Gut Project actually was an international study and included like 52 territories and countries across the globe, especially the United States and the U.K., And it was the first time that they had microbiome samples for over 10,000 people and simultaneously all kinds of information about their diet, their lifestyle. What were they eating? How were they eating?

What was their dietary pattern? All these different things. And when they did their analysis, this was like purely statistical. This was not some sort of a priori thing they were trying to find. When they did their analysis, this thing jumped out. It jumped out off the charts where they go, whoa, that's the thing. And the answer was eating at least 30 unique plants per week.

What was their dietary pattern? All these different things. And when they did their analysis, this was like purely statistical. This was not some sort of a priori thing they were trying to find. When they did their analysis, this thing jumped out. It jumped out off the charts where they go, whoa, that's the thing. And the answer was eating at least 30 unique plants per week.

What was their dietary pattern? All these different things. And when they did their analysis, this was like purely statistical. This was not some sort of a priori thing they were trying to find. When they did their analysis, this thing jumped out. It jumped out off the charts where they go, whoa, that's the thing. And the answer was eating at least 30 unique plants per week.