Dr. Will Bulsiewicz

I also would call it increased intestinal permeability. When the gut barrier is damaged and broken, this lipopolysaccharide gets into the bloodstream. So if you draw blood on a person and you're seeing, oh man, their LPS is spiking, you know the gut barrier has been harmed. All right. And in the study, they basically gave people a significant amount of alcohol.

I also would call it increased intestinal permeability. When the gut barrier is damaged and broken, this lipopolysaccharide gets into the bloodstream. So if you draw blood on a person and you're seeing, oh man, their LPS is spiking, you know the gut barrier has been harmed. All right. And in the study, they basically gave people a significant amount of alcohol.

It was not one drink, a significant amount of alcohol. But here's what happened. Their blood alcohol level went up in parallel. Their lipopolysaccharide level went up. The lipopolysaccharide did not normalize until the alcohol normalized.

It was not one drink, a significant amount of alcohol. But here's what happened. Their blood alcohol level went up in parallel. Their lipopolysaccharide level went up. The lipopolysaccharide did not normalize until the alcohol normalized.

It was not one drink, a significant amount of alcohol. But here's what happened. Their blood alcohol level went up in parallel. Their lipopolysaccharide level went up. The lipopolysaccharide did not normalize until the alcohol normalized.

So the fact that these things happened in parallel, the fact that you couldn't get LPS to get out of the bloodstream until the alcohol was also gone, to me provides the suggestion that we're better off without alcohol in our lives.

So the fact that these things happened in parallel, the fact that you couldn't get LPS to get out of the bloodstream until the alcohol was also gone, to me provides the suggestion that we're better off without alcohol in our lives.

So the fact that these things happened in parallel, the fact that you couldn't get LPS to get out of the bloodstream until the alcohol was also gone, to me provides the suggestion that we're better off without alcohol in our lives.

Yeah. I'll still have a drink once in a while if I'm being social. But like as a dad with four kids, I'm not out doing that very much.

Yeah. I'll still have a drink once in a while if I'm being social. But like as a dad with four kids, I'm not out doing that very much.

Yeah. I'll still have a drink once in a while if I'm being social. But like as a dad with four kids, I'm not out doing that very much.

But the one thing I would say with caution, though, is that as alcohol use has gone down, marijuana use has come up. And people want to believe that there's no risk associated with that. That is certainly not true. So a few things. First of all, cognitively, it definitely affects people's brains. We call them potheads back in the 90s, right?

But the one thing I would say with caution, though, is that as alcohol use has gone down, marijuana use has come up. And people want to believe that there's no risk associated with that. That is certainly not true. So a few things. First of all, cognitively, it definitely affects people's brains. We call them potheads back in the 90s, right?

But the one thing I would say with caution, though, is that as alcohol use has gone down, marijuana use has come up. And people want to believe that there's no risk associated with that. That is certainly not true. So a few things. First of all, cognitively, it definitely affects people's brains. We call them potheads back in the 90s, right?

There's actually studies now where they look at the size of the brain on imaging and have shown that the brain shrinks with chronic marijuana use. I don't like the sound of that.

There's actually studies now where they look at the size of the brain on imaging and have shown that the brain shrinks with chronic marijuana use. I don't like the sound of that.

There's actually studies now where they look at the size of the brain on imaging and have shown that the brain shrinks with chronic marijuana use. I don't like the sound of that.

Okay. And then in the gastroenterology world, 10 or 12 years ago, If you ever made the diagnosis that I'm about to share, your peers would look at you like you are a genius. But there has been the emergence in recent years of something called cannabinoid hyperemesis syndrome. People may have also heard of this being referred to as cyclic vomiting syndrome.

Okay. And then in the gastroenterology world, 10 or 12 years ago, If you ever made the diagnosis that I'm about to share, your peers would look at you like you are a genius. But there has been the emergence in recent years of something called cannabinoid hyperemesis syndrome. People may have also heard of this being referred to as cyclic vomiting syndrome.

Okay. And then in the gastroenterology world, 10 or 12 years ago, If you ever made the diagnosis that I'm about to share, your peers would look at you like you are a genius. But there has been the emergence in recent years of something called cannabinoid hyperemesis syndrome. People may have also heard of this being referred to as cyclic vomiting syndrome.