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Dr. Yara Haridi

๐Ÿ‘ค Speaker
906 total appearances

Appearances Over Time

Podcast Appearances

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

If the odontode has nerves going to it, then at least that's step one of it being innervated.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

And these odontodes in our early fish from the middle Ordovician have pulp cavities and pulp cavities are where the nerve goes.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

And we were able to trace it all the way down to know that like there had to have been a nerve there.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

But do modern odontodes outside the mouth have nerves?

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

So went, collected a bunch of these algae-eating plecos, learned how to keep an aquarium because God knows I never had an aquarium, and bred a bunch of these little fish.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

And then we use this amazing method called clarity where you make the little embryos super clear.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

You basically remove all the...

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

Fats and lots of the proteins.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

And then you add antibodies that attach only to nerves.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

And then they have a fluorescent probe.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

So they glow under a microscope.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

So you bathe them in these antibodies and put them under the microscope.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

And then they glow wherever the nerves go.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

And you can trace every nerve to every odontoid.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

All their odontoids were innervated right into the pulp cavity.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

They have chikadontodes that are on this like... Catfish are really weird, guys.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

I'm just going to side note everybody.

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

I think, what is it?

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

One in five vertebrates is a catfish?

Ologies with Alie Ward
Paleohistology (WHY TEETH EXIST) with Yara Haridy

Their diversity is wild.