Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Pricing

Drew Endy

πŸ‘€ Person
71 total appearances

Appearances Over Time

Podcast Appearances

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

I love it.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

And then the thing that makes proteins, the ribosomeβ€”

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

This molecular machine that makes proteins from genetic instructions, that's going to be about as tall as a person.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

And then the DNA, the inside cells is DNA, the genome, the genetic instructions.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

That DNA for our cell is going to go back and forth across the cell over a thousand times.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

If the building's 100 meters long...

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

The DNA is going to be kilometers long, and it's going to be coiled up and wrapped up and packed inside the cell.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

And then another thing that shows up is if you're inside a cell in this building, the building's going to be packed maybe 20% to 40% of stuff.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

Wow.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

It's like a hoarder of molecules.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

Imagine a bookstore that's 50% full of books almost, and you could just barely move through it.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

All right.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

Now, there's one more wrinkle that blows my mind.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

The molecules inside the cell are moving.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

They're not fixed in one position, and they're moving spontaneously automatically.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

because the molecules are free to move due to the energy of the system.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

And so that protein that's a little basketball in this big building is moving so fast

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

it's able to go through the entire building within a second.

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

And so that's what's incredibly interesting to me when we start to think about how are these systems working?

Short Wave
Synthetic Cells: The Next Bioengineering Frontier

How are these cells making other cells?