Dylan Gemelli
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Welcome back to the Dylan Gemelli podcast. So today I'm going to give a breakdown of what is becoming one of the more popular peptides out there. And that is AOD 9604, which stands for anti-obesity drug 9604. So what I want to do, I want to give a breakdown of everything that I can possibly think of that would need to be conveyed to give a proper education on what AOD actually is. We're
Welcome back to the Dylan Gemelli podcast. So today I'm going to give a breakdown of what is becoming one of the more popular peptides out there. And that is AOD 9604, which stands for anti-obesity drug 9604. So what I want to do, I want to give a breakdown of everything that I can possibly think of that would need to be conveyed to give a proper education on what AOD actually is. We're
what you can expect from it. But then I also want to look at it as maybe a possible alternative to GLP-1 use. Some people like to run them together. I just want to get into everything AOD 9604. I get a ton of questions about it. And a lot of people that have me on their shows, their podcasts, they like to bring me on to discuss peptides.
what you can expect from it. But then I also want to look at it as maybe a possible alternative to GLP-1 use. Some people like to run them together. I just want to get into everything AOD 9604. I get a ton of questions about it. And a lot of people that have me on their shows, their podcasts, they like to bring me on to discuss peptides.
So I want to try to give everybody nice, thorough breakdowns of each compound, especially the ones that are becoming more popular. So like I said, anti-obesity drug 9604, it's actually just a synthetic peptide fragment. Now it's derived from the C-terminal end of human growth hormone.
So I want to try to give everybody nice, thorough breakdowns of each compound, especially the ones that are becoming more popular. So like I said, anti-obesity drug 9604, it's actually just a synthetic peptide fragment. Now it's derived from the C-terminal end of human growth hormone.
So initially it was developed to combat obesity, but people are starting to know it for its ability to promote fat loss, boosting metabolic function, supporting joint health. But the beauty of this is you're getting all of this without the adverse effects that you normally see when you use exogenous HGH.
So initially it was developed to combat obesity, but people are starting to know it for its ability to promote fat loss, boosting metabolic function, supporting joint health. But the beauty of this is you're getting all of this without the adverse effects that you normally see when you use exogenous HGH.
So unlike using HGH, when you use AOD, you're not going to have a negative effect on your blood sugar or your insulin sensitivity. And it's not going to cause growth in your organs or tissues like HGH certainly can. So what does it do? Well, it selectively targets lipolytic activity.
So unlike using HGH, when you use AOD, you're not going to have a negative effect on your blood sugar or your insulin sensitivity. And it's not going to cause growth in your organs or tissues like HGH certainly can. So what does it do? Well, it selectively targets lipolytic activity.
So that makes it a much safer and a more targeted solution for people that really want to get sustainable weight loss and are looking to improve their metabolic health. Now, I want to talk about how it actually works. So a lot of times what I find is that people don't explain mechanism of action. They'll just tell you, well, it burns fat or it does this for your possibly increasing your hunger.
So that makes it a much safer and a more targeted solution for people that really want to get sustainable weight loss and are looking to improve their metabolic health. Now, I want to talk about how it actually works. So a lot of times what I find is that people don't explain mechanism of action. They'll just tell you, well, it burns fat or it does this for your possibly increasing your hunger.
It heals you. But why? How? So let's get into that. So one is it's going to increase your metabolic rate. But the beauty of that is without muscle loss. So it's going to enhance your metabolic efficiency by a few ways. First, it's going to upregulate fat metabolizing enzymes. It's going to increase your caloric expenditure while you're resting, but it's going to spare lean muscle mass.
It heals you. But why? How? So let's get into that. So one is it's going to increase your metabolic rate. But the beauty of that is without muscle loss. So it's going to enhance your metabolic efficiency by a few ways. First, it's going to upregulate fat metabolizing enzymes. It's going to increase your caloric expenditure while you're resting, but it's going to spare lean muscle mass.
That's a really big factor in long-term weight management. Now, this is in contrast to a lot of typical weight loss approaches that we see, and it it oftentimes you see with GLP ones, especially people losing a lot of weight really fast, but it's not sustainable and they're sacrificing a lot of muscle, which is very, very damaging to your long-term health. Now it,
That's a really big factor in long-term weight management. Now, this is in contrast to a lot of typical weight loss approaches that we see, and it it oftentimes you see with GLP ones, especially people losing a lot of weight really fast, but it's not sustainable and they're sacrificing a lot of muscle, which is very, very damaging to your long-term health. Now it,
also activates fat burning receptors. So it functions by stimulating the beta-3 receptors found in adipose fat tissue. And these are key regulators of lipolysis. Now, lipolysis, for those of you that don't know, is just the process of breaking down stored fat.
also activates fat burning receptors. So it functions by stimulating the beta-3 receptors found in adipose fat tissue. And these are key regulators of lipolysis. Now, lipolysis, for those of you that don't know, is just the process of breaking down stored fat.
Now, once it's activated, these receptors are going to initiate the conversion of triglycerides into free fatty acids and glycerol, which are then used for energy production. It also supports insulin sensitivity. Now, this is key here. So there's a lot of evidence out there that says that AOD may also improve insulin sensitivity. And what can that potentially do?
Now, once it's activated, these receptors are going to initiate the conversion of triglycerides into free fatty acids and glycerol, which are then used for energy production. It also supports insulin sensitivity. Now, this is key here. So there's a lot of evidence out there that says that AOD may also improve insulin sensitivity. And what can that potentially do?