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Eric Topol

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
3037 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Is that a good way to summarize it?

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Well, some people might know Chicago for deep dish pizza, but I know it for sensor pioneering work.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Yeah, and by the way, if you have questions that you want to ask, Shana, please put them in the message, and we'll try to make sure that we respond to them as we're talking.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Now, besides the consortium you have that has taken on this work,

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

You mentioned something that's really important is the AI side of it.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

One of the most difficult things in AI is the analysis of data from continuous sensors.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

The words that are used are time series analysis.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

So in order, you know, there's so much data that's generated.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

People think the genome has got a lot of data.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Well, you have a continuous sensors going on and you're trying to analyze that with all the other layers of a person data.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

So have you been working on how to do that type of analytic work?

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Because that's another part of the challenge.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Yeah, I couldn't agree with you more.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

I mean, the ability to take the analytics to inform an individual about, you know, that they could be having impending heart failure, that they're having high levels of inflammation, that something is off track, you know, to have that do that reliably so they're not getting false signals, you know, it's another part of the challenge beyond what you've already done, which is really quite extraordinary.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

Now, what's also amazing about you is that this is only one of the dimensions of your work.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

I was looking at your recent publications and it is, you know, you've got all this work on rare cells, lymphocytes and macrophages.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

You've got, you know, many different aspects of what you're doing that are apart from this.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

So maybe you can just fill us in that this is just, maybe this is the principle part that's got you most excited, but you're using, because you have molecular probes, um,

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

you know, in the live person, or at this point, perhaps you say models, you're going in directions for intracellular delivery.

Ground Truths
Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time

I mean, wow.