Hamilton Morris

Right. So I think that would be my first guess would be, you know, is this really somebody that's locked out or maybe they are just not really smoking it and getting the hits or for whatever reason. Yeah. And, To even begin to assess that, you'd want to do something like give them an IV bolus dose of DMT to see if they're truly unresponsive, I sort of suspect.

Right. So I think that would be my first guess would be, you know, is this really somebody that's locked out or maybe they are just not really smoking it and getting the hits or for whatever reason. Yeah. And, To even begin to assess that, you'd want to do something like give them an IV bolus dose of DMT to see if they're truly unresponsive, I sort of suspect.

Right. So I think that would be my first guess would be, you know, is this really somebody that's locked out or maybe they are just not really smoking it and getting the hits or for whatever reason. Yeah. And, To even begin to assess that, you'd want to do something like give them an IV bolus dose of DMT to see if they're truly unresponsive, I sort of suspect.

Because even in these DMT-X experiments where they give people DMT repeatedly over long periods of time, the accumulation of tolerance is very minimal. It does occur, but it's very minor. So the idea that somebody would... have some kind of total tolerance outside of an extreme situation. Like they were smoking it all day, every day for like three months or something. It just seems unlikely.

Because even in these DMT-X experiments where they give people DMT repeatedly over long periods of time, the accumulation of tolerance is very minimal. It does occur, but it's very minor. So the idea that somebody would... have some kind of total tolerance outside of an extreme situation. Like they were smoking it all day, every day for like three months or something. It just seems unlikely.

Because even in these DMT-X experiments where they give people DMT repeatedly over long periods of time, the accumulation of tolerance is very minimal. It does occur, but it's very minor. So the idea that somebody would... have some kind of total tolerance outside of an extreme situation. Like they were smoking it all day, every day for like three months or something. It just seems unlikely.

It seems like the more likely explanation is that they're just not smoking it right. But again, this speaks to the mythology and the mysticism surrounding a lot of these substances. Like I'm sympathetic to that. There's something kind of strange about them and it's, they don't always lend themselves to the most analytical interpretations.

It seems like the more likely explanation is that they're just not smoking it right. But again, this speaks to the mythology and the mysticism surrounding a lot of these substances. Like I'm sympathetic to that. There's something kind of strange about them and it's, they don't always lend themselves to the most analytical interpretations.

It seems like the more likely explanation is that they're just not smoking it right. But again, this speaks to the mythology and the mysticism surrounding a lot of these substances. Like I'm sympathetic to that. There's something kind of strange about them and it's, they don't always lend themselves to the most analytical interpretations.

Yes. It was like first discovered synthetically. Yeah. Yeah. It was Mansky did the first synthesis in Canada as a potential reference for a like strawberry plant alkaloid before it had been found in nature. Yeah.

Yes. It was like first discovered synthetically. Yeah. Yeah. It was Mansky did the first synthesis in Canada as a potential reference for a like strawberry plant alkaloid before it had been found in nature. Yeah.

Yes. It was like first discovered synthetically. Yeah. Yeah. It was Mansky did the first synthesis in Canada as a potential reference for a like strawberry plant alkaloid before it had been found in nature. Yeah.

And I do believe that, but the paradox is that it's simultaneously, uh, all natural and all synthetic, depending on how you want to think about it.

And I do believe that, but the paradox is that it's simultaneously, uh, all natural and all synthetic, depending on how you want to think about it.

And I do believe that, but the paradox is that it's simultaneously, uh, all natural and all synthetic, depending on how you want to think about it.

They're both the same. And... Somebody will say, oh, but there's a difference between, for example, toad-derived 5-MeO-DMT and synthetic 5-MeO-DMT. And I've often said, well, okay, if there's no chemical difference, then there can't be a difference. But this does neglect the psychological contribution of the user.

They're both the same. And... Somebody will say, oh, but there's a difference between, for example, toad-derived 5-MeO-DMT and synthetic 5-MeO-DMT. And I've often said, well, okay, if there's no chemical difference, then there can't be a difference. But this does neglect the psychological contribution of the user.

They're both the same. And... Somebody will say, oh, but there's a difference between, for example, toad-derived 5-MeO-DMT and synthetic 5-MeO-DMT. And I've often said, well, okay, if there's no chemical difference, then there can't be a difference. But this does neglect the psychological contribution of the user.

This, again, comes back to the expectation, beliefs, what you project onto the experience. So then if the case is that there is a difference and that difference is not derived from the chemistry of the substance, but from the psychological expectation of the user, then why can't you reformulate your expectation accordingly so that you have the same associations with the synthetic substance?

This, again, comes back to the expectation, beliefs, what you project onto the experience. So then if the case is that there is a difference and that difference is not derived from the chemistry of the substance, but from the psychological expectation of the user, then why can't you reformulate your expectation accordingly so that you have the same associations with the synthetic substance?