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Helen MacDonald

👤 Person
1132 total appearances

Appearances Over Time

Podcast Appearances

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And to think that there could be sort of waste going on at a time when people are very busy.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Yeah, we talked back, I think, in our first COVID podcast, which I think was in February, about the blank canvas of evidence that we currently had on the virus and the illness COVID-19.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And a lot of information has now been thrown at that canvas very quickly.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And we've talked quite a bit about descriptive papers and, for example, case series that have come out looking at people with varying severity of COVID-19 and looking back to describe their characteristics.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And we've learned things like more severe cases have been older people, have been men.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

in people with cardiac disease, but we haven't discussed much looking forwards and seen sort of prognostic research where you might look at a variable or risk factor and assess the influence of that on the outcome.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And that would seem to be useful to those who might need to be making policies around how to offer escalation of care into hospital or into intensive care units, particularly when resources are scarce.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

So the research team were really interested to get this fast track paper in

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

which was a systematic review and critical appraisal of prediction models for diagnosis and prognosis in COVID-19.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And a few days ago, I spoke with Laura Weintz and Martin Van Smaeden, two of its key authors.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

So let's hear from them.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

So one thing that we've asked Laura and Martin to do is to keep updating this systematic review for us.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And one of the things I wanted to talk a little bit about is innovation in journals.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Journals feel like a bit of a stuffy old place at times.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

But we've been increasingly thinking about how we can make the evidence that we publish a little bit more live.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

I don't know yet that we're going to be able to create this as a living systematic review, but we're going to give it a go.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

There's quite a few technical challenges, but we're going to work on it over the coming weeks and months.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

And maybe we'll come back to Laura and Martin and hear if there is any success in terms of creating some models or spotting some new ones out there.

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

You're starting this, Carl, are you?

Talk Evidence
Talk Evidence covid-19 update - hydroxy/chloroquinine, prognostic models and facemaskss

Well, being quite radical this week...