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Helen MacDonald

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
1132 total appearances

Appearances Over Time

Podcast Appearances

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

So assuming we do all that well, that we do take our tests with good technique and we do take them at the right time or we repeat them so that we get another shot at identifying.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Do we know anything about the diagnostic accuracy of these tests in terms of that slightly frightening two by two diagnostic accuracy table, which clinicians tend to feel slightly nervous of looking at?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And which of those boxes are we feeling sort of worried about in terms of this test performing or not?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And that testing that they've been doing with the

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

with the PCR test, they're looking at people who have some kind of symptom that makes them concerned they have COVID or they've had a particular exposure, and then they're being tested.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Are they also testing then the contacts or household contacts of those people to understand whether they've had the condition?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Or is it just the sort of index cases, if that's the right term?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

So when we move into that phase of trying to work out how many people have had the infection and we're looking more at using the antibody test, which of those sensitivity and specificity measures are you most bothered about then?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And how about moving to answer different questions?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

There are people out there perhaps caring for vulnerable groups of people who are perhaps being shielded at the moment.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

And there are also concerns from healthcare workers who are

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

perhaps older, maybe in their 50s or 60s or have comorbidities or are pregnant and for whom knowing that they have either had the condition or not may influence their ability then to go and care for people.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

What would we be looking at doing there?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

But we have to come to what about the diagnostic test?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

characteristics of these tests for helping out individuals.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

So for helping out those healthcare workers who perhaps now don't have symptoms, maybe they've been some of the, what is it, a fifth or a quarter of the population that have been in self-isolation or quarantine because they've had family members affected.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

who potentially could return to work or other members of the population caring for vulnerable people.

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Do you think though there are issues around the performance of particularly the antibody tests in those populations or is the information that we're seeing showing that they are sufficiently sensitive and have sufficient specificity to be reliable there?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

So you mean you get expertise using one of these tests and you just stick with that sort of provider or that manufacturer?

Talk Evidence
Talk Evidence covid-19 update - pneumonia, guidelines, preprints and testing

Goodbye from me.