Hosseini Manji
👤 PersonAppearances Over Time
Podcast Appearances
When I first brought up the idea, I think understandably people had some reservations because ketamine has sometimes been used as a club drug. So I had to really sort of walk through a lot of the reasons why I thought this would be successful.
Yeah, I think it's fair to say that it was done in stages. So, you know, the initial discussions centered around, look, we think this is a good idea. Let's go ahead and generate some of the data.
Yeah, I think it's fair to say that it was done in stages. So, you know, the initial discussions centered around, look, we think this is a good idea. Let's go ahead and generate some of the data.
Yeah, I think it's fair to say that it was done in stages. So, you know, the initial discussions centered around, look, we think this is a good idea. Let's go ahead and generate some of the data.
It's like an inhaler, except it's delivered through the nose. Basically, the person comes into the clinic, their dose is calculated, and they self-administer it. So they administer it in the nose themselves, and then there's no drug left in the device, so you throw away the device.
It's like an inhaler, except it's delivered through the nose. Basically, the person comes into the clinic, their dose is calculated, and they self-administer it. So they administer it in the nose themselves, and then there's no drug left in the device, so you throw away the device.
It's like an inhaler, except it's delivered through the nose. Basically, the person comes into the clinic, their dose is calculated, and they self-administer it. So they administer it in the nose themselves, and then there's no drug left in the device, so you throw away the device.
Sure. So it's basically two side effects. One is that you get a slight increase in blood pressure after you take it. And it's about the blood pressure increase that you or I might have if we ran up a flight of stairs. The second thing is something called dissociation. So what dissociation is, that you might feel that the colors around you are brighter or the sounds are louder, etc.
Sure. So it's basically two side effects. One is that you get a slight increase in blood pressure after you take it. And it's about the blood pressure increase that you or I might have if we ran up a flight of stairs. The second thing is something called dissociation. So what dissociation is, that you might feel that the colors around you are brighter or the sounds are louder, etc.
Sure. So it's basically two side effects. One is that you get a slight increase in blood pressure after you take it. And it's about the blood pressure increase that you or I might have if we ran up a flight of stairs. The second thing is something called dissociation. So what dissociation is, that you might feel that the colors around you are brighter or the sounds are louder, etc.
For almost everyone, you know, it sort of starts within about half an hour. At about one hour, it's gone. Dissociation, is that like tripping? I think so. I think it's a low, low level tripping. Very low level. Very low level tripping.
For almost everyone, you know, it sort of starts within about half an hour. At about one hour, it's gone. Dissociation, is that like tripping? I think so. I think it's a low, low level tripping. Very low level. Very low level tripping.
For almost everyone, you know, it sort of starts within about half an hour. At about one hour, it's gone. Dissociation, is that like tripping? I think so. I think it's a low, low level tripping. Very low level. Very low level tripping.
You know, we got the call while the whole team was together, and obviously we celebrated right after.
You know, we got the call while the whole team was together, and obviously we celebrated right after.
You know, we got the call while the whole team was together, and obviously we celebrated right after.
Okay.
Okay.
Okay.
I think there's no doubt it's opened the door. I would say both, you know, sort of this different type of treatment. And then what Spravato has also been able to do is, you know, sort of normalize to some extent the in-clinic administration. So I think that's one of the things that until Spravato came along, that simply wasn't the case. So I think it certainly has opened the door.