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Hudson Freeze

Appearances

Radiolab

The Age of Aquaticus

1099.433

The stuff of which all life is made.

Radiolab

The Age of Aquaticus

116.417

Well, let's see. I was born in a small railroad town in Indiana. And as a junior in high school, I spent some time at Indiana University. It's thrilling, you know, for somebody who hasn't seen more than a two-story building before. This was a big deal. And I met faculty people there.

Radiolab

The Age of Aquaticus

149.603

And so when he graduated from high school... I came back to Indiana University and I was able to get in the bacteriology department. And he really wanted to work with one scientist named Dr. Thomas Brock. I had heard him give a lecture before about mating types in yeast. And, you know, anytime you're talking about mating types in college, you know, you're going to be a hit.

Radiolab

The Age of Aquaticus

1509.055

As you might call it, TAC polymerase.

Radiolab

The Age of Aquaticus

1587.122

We're here to celebrate the completion of the first survey of the entire human genome.

Radiolab

The Age of Aquaticus

1596.068

And from there on out... I would say every biotechnology company in the world... Every lab anywhere that's studying DNA... Has to use PCR.

Radiolab

The Age of Aquaticus

171.516

And so anyway, I go down to see him thinking I'm going to work on mating types. And he says, well, we're not working on mating types anymore, but we are going to Yellowstone National Park to look into the hot springs for bacteria.

Radiolab

The Age of Aquaticus

1741.202

And the critical component is the TAC polymerase.

Radiolab

The Age of Aquaticus

1751.019

But that isn't why you do the science, right?

Radiolab

The Age of Aquaticus

1753.541

I realized it was a critical component and that that was sort of payoff in itself.

Radiolab

The Age of Aquaticus

1759.808

To know that my contribution really counted.

Radiolab

The Age of Aquaticus

1813.54

It's really, really beautiful work. It took a long time before I was able to use TAC and, you know, really make a difference for individuals and keep people alive that likely would have died. It's funny how 1966 was a real turning point.

Radiolab

The Age of Aquaticus

233.348

That's right. And so he had a small, relatively small grant in basic science. A grant of $80,000 from the U.S. government. To go out and see what he could find.

Radiolab

The Age of Aquaticus

247.683

And I thought, that's perfect. You know, I had done before it was Mars and it's cold there. You know, now I'm going to go to the complete opposite. I'm going to go where it's boiling hot.

Radiolab

The Age of Aquaticus

263.169

Because I had never been west of Chicago. So he hops on a train. I got on in Garrett, Indiana, and then went through Chicago. That's where I picked up the train that went nonstop.

Radiolab

The Age of Aquaticus

291.961

I said, boy, those are funny-looking clouds. Oh, my God, those are not clouds, man. They're mountains. They're real mountains. It's just like mountains that you see in the cowboy shoes. You know, I mean, I was just, I was really thrilled to be able to see this kind of stuff. Oh, I'm really getting out there. So, I mean, it was just a great trip.

Radiolab

The Age of Aquaticus

314.468

So I get off in Billings, Montana, and take a bus to West Yellowstone. That's where the lab was set up in this little cabin, you know, a kitchen and sort of a living room. But it was sparse. You know, you wouldn't advertise it as a lab in these days. It looked more like, you know, where Ted Kaczynski might hang out.

Radiolab

The Age of Aquaticus

339.995

It was a shack. Yeah. Anyway, Brock and his crew. You know, we get going at about 7 o'clock, something like that.

Radiolab

The Age of Aquaticus

373.742

Yeah. You start out more yellowish and then the orange would start coming through.

Radiolab

The Age of Aquaticus

407.621

And... We would take these glass slides that had nothing on them, put them in the spring. So if there were any organisms that were bubbling up out of the interior of the earth, they might be able to attach.

Radiolab

The Age of Aquaticus

487.438

So I had a whole series of different tubes at different temperatures.

Radiolab

The Age of Aquaticus

50.186

Hudson Freeze. Dr. Freeze. You know, there have been a lot of comments on that. What's Freeze doing working on hot stuff, right?

Radiolab

The Age of Aquaticus

509.412

So every day I would go in there and I'd look to see if there was anything that looked like it might be growing.

Radiolab

The Age of Aquaticus

517.737

And the darn things could run dry.

Radiolab

The Age of Aquaticus

521.76

Running up the electric bill of the microbiology department.

Radiolab

The Age of Aquaticus

530.984

Always looking for a change in the soup. If bacteria were growing, it would be cloudy. It might even start to smell a little bit.

Radiolab

The Age of Aquaticus

551.752

I couldn't find anything. And then on the fourth, maybe fifth day, September 19th, 1966. He picks up one of the vials. I just tapped it with my finger, and there was all this swirly stuff that came up. I mean, it looked like diamonds kind of running around. It was like all around inside the tube. And I thought, oh, my God, maybe this is it.

Radiolab

The Age of Aquaticus

599.071

At almost boiling water.

Radiolab

The Age of Aquaticus

611.76

And I said, I said, oh my God, I am the first person in the world ever to see this. The next day, I'm telling everybody in the lab what I'm telling Tom Brock. And one of the guys in the lab says, well, I think we ought to call it Hedsonii freesiensis.

Radiolab

The Age of Aquaticus

646.841

Can't name them after people anymore.

Radiolab

The Age of Aquaticus

660.546

I'm going around the labs. It is the dawning of the age of Aquaticus. Age of Aquaticus.

Radiolab

The Age of Aquaticus

685.077

I mean, that's why we can't go out and, you know, sit at 180 degrees because our proteins fall apart. Our enzymes fall apart.

Radiolab

The Age of Aquaticus

724.221

Yeah. You know, this was the thing that led us to say, well, what if you go down 5,000 feet under the sea where we know there are volcanoes down there? Boy, I'll bet nothing lives down there. Well, yes, it does.

Radiolab

The Age of Aquaticus

753.774

Yeah. Life will still continue to exist as long as you have liquid water. That, if I had to pick anything, is really the sort of lesson of this. Life will exist anywhere where there's nutrients. It will go any place where it can find energy to use energy to grow. I'm going to quote Jeff Goldblum here. Life finds a way. Life finds a way.

Radiolab

The Age of Aquaticus

796.656

And he's like, no. It has no use. It has absolutely no use. You know, it's curiosity. I mean, it's science for science's sake. It's fundamental research. That's the way science goes.

Radiolab

The Age of Aquaticus

837.654

He said, this is like this. And I want to talk to you about a science prize. And I thought, oh, my God, it's the prize patrol. If I sign up for, you know, Scientific American for six years at this bargain rate, I'm going to get a, you know, something in the mail.