James Menendez

So we prepare normal, healthy copies of the gene in the laboratory, are able to package these into virus particles, disabled virus particles, which can be safely injected into the eye and targeted to the retina, to the cells that are needing those genes.

Absolutely. So these kids would normally expect to see very little, let's say, at light and dark at birth, and they lose that sight very quickly.

Absolutely. So these kids would normally expect to see very little, let's say, at light and dark at birth, and they lose that sight very quickly.

But children like Jace and these other children we've treated have shown really remarkable improvements in sight to the extent where they can navigate safely, they can run around without bumping into things, they can play with their friends, pick up small objects off the floor.

But children like Jace and these other children we've treated have shown really remarkable improvements in sight to the extent where they can navigate safely, they can run around without bumping into things, they can play with their friends, pick up small objects off the floor.

This is a particularly rare condition, but what's important is that it shows that this approach can help in a condition that's really very, very severe. The hope is that this will give further confidence that this sort of approach, this treatment, can offer hope to people, to children with more common blinding diseases.

This is a particularly rare condition, but what's important is that it shows that this approach can help in a condition that's really very, very severe. The hope is that this will give further confidence that this sort of approach, this treatment, can offer hope to people, to children with more common blinding diseases.

Absolutely. This is a very rare condition. In fact, we already have a genetic treatment for a similar condition, which is less mild. But as I say, this particular condition is more severe. and the improvements are really spectacular.

Absolutely. This is a very rare condition. In fact, we already have a genetic treatment for a similar condition, which is less mild. But as I say, this particular condition is more severe. and the improvements are really spectacular.

Given the impressive changes we've seen so far in these four children and indeed in additional children who have subsequently been treated, we're very hopeful that marketing will be possible and that licensing will enable the treatment to be available to other children very soon.

Given the impressive changes we've seen so far in these four children and indeed in additional children who have subsequently been treated, we're very hopeful that marketing will be possible and that licensing will enable the treatment to be available to other children very soon.

Not many people say no to Donald Trump. President Zelensky has, and now he's paying the price. At the heart of Mr Trump's fury is a row over Ukraine's critical minerals. Mr Zelensky floated the idea last year as part of his so-called peace plan that Ukraine might offer American firms access to its rare earth deposits in return for continued US military support.

Not many people say no to Donald Trump. President Zelensky has, and now he's paying the price. At the heart of Mr Trump's fury is a row over Ukraine's critical minerals. Mr Zelensky floated the idea last year as part of his so-called peace plan that Ukraine might offer American firms access to its rare earth deposits in return for continued US military support.

Last weekend at a conference in Munich, Mr Trump's team laid down an ultimatum. Ukraine should, it was reported, sign over 50% not only of its mineral wealth but also its oil and gas reserves and infrastructure. Mr Trump claims inaccurately that America is owed $500 billion for its previous assistance to Ukraine. Critics accuse Mr Trump of seeking war reparations from the wrong side.

Last weekend at a conference in Munich, Mr Trump's team laid down an ultimatum. Ukraine should, it was reported, sign over 50% not only of its mineral wealth but also its oil and gas reserves and infrastructure. Mr Trump claims inaccurately that America is owed $500 billion for its previous assistance to Ukraine. Critics accuse Mr Trump of seeking war reparations from the wrong side.

Well, Mr. Zelensky rejected this US demand out of hand, saying any deal had to be linked to post-war security guarantees. This is not a serious conversation, he said today. I am defending Ukraine. I cannot sell my country. There is much at stake. Ukraine has vast reserves of mineral deposits. How much is not clear, but some estimates value them at more than $11 trillion.

Well, Mr. Zelensky rejected this US demand out of hand, saying any deal had to be linked to post-war security guarantees. This is not a serious conversation, he said today. I am defending Ukraine. I cannot sell my country. There is much at stake. Ukraine has vast reserves of mineral deposits. How much is not clear, but some estimates value them at more than $11 trillion.

They include things like lithium, graphite, cobalt and titanium, which are used in everything from mobile phones and renewable energy to missiles and superconductors. But these minerals are rare and China dominates the market. Donald Trump may say he wants peace in Ukraine, but he also wants a peace of Ukraine. And right now, President Zelensky is not playing ball.

They include things like lithium, graphite, cobalt and titanium, which are used in everything from mobile phones and renewable energy to missiles and superconductors. But these minerals are rare and China dominates the market. Donald Trump may say he wants peace in Ukraine, but he also wants a peace of Ukraine. And right now, President Zelensky is not playing ball.

As two major powers discussed the future of his country elsewhere, in Turkey a visibly irritated President Zelensky highlighted what he saw as the flaws with his country's exclusion from this first stage of talks.