Jared Tangney

But I went for a run beforehand, right?

And if I go for a run, if I run for five miles afterwards, I can eat a bagel and my glucose won't rise nearly as high.

So it's all of that contextual information that's really insightful.

Yeah, it was far from overnight, that's for sure.

So, I mean, the original concept came from looking at the drug delivery space, actually.

So if you look at drug delivery, what the literature shows is that if you deliver something like insulin, for example, into the skin, the body absorbs it very quickly.

Versus if you deliver it into the subcutaneous tissue, it takes quite a bit longer.

So this initial theory was...

well, hey, if the body absorbs things like drugs more quickly in the skin, we should be able to measure things in the skin as well.

And the reason for that is you're right next to this capillary bed that basically perfuses all of our skin, right?

So all of our thermoregulation happens through this capillary bed in our skin.

So for example, when you're out for a run and your body is trying to cool off, those blood vessels dilate and therefore your body can...

can get rid of that heat more easily.

And so we've got this really nice capillary bed that's about a millimeter below the surface of the skin.

And so our thought was if we can measure close to that capillary bed, it should be a really good location for sensing.

And so that was the initial concept.

And the first years were really around proving that dermal sensing is viable, that you could actually measure in the skin and then it correlates well with the blood.

Sometimes the conventional wisdom would be, oh, well, hey, if you're not as deep in the body, maybe this doesn't correlate as well with the blood.

But because we're right next to this capillary bed, it's the opposite.

Yeah.