TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
What if I told you that the pandemic will save the lives of millions of people?
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
It's a difficult thing to consider, given how many loved ones we've already lost.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
But throughout the course of human history, massive public health crises have resulted in innovation in healthcare and technology.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
For example, the Black Death gave rise to the Gutenberg Press,
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
And the 1918 flu pandemic led to modern vaccine technology.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
The COVID-19 pandemic has and will be no different.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
Just look at our vaccines, normally developed over many years, and the mRNA vaccines were deployed in a mind-blowing 11 months.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
How is that even possible?
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
It was possible because scientists have been working for many years to get us to the point where we could use mRNA quickly in an emergency situation.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
Specifically, we've been working on how to help mRNA with its biggest problem, which is that it doesn't normally go to the right places inside of our bodies.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
Fortunately, we got around that problem just in time, and I'd like to tell you about the technology that we used to do it.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
When mRNA is administered, it's injected into our muscles or our bloodstream, but we actually need it to go inside of our cells.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
Unfortunately, mRNA is fragile, and our bodies will destroy it before it goes very far.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
You can think of mRNA like a glass vase that you'd like to send in the mail.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
Without a box and bubble wrap, it'll break long before it's been delivered.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
And without an address on the box,
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
your postal delivery service will have no idea where to take it.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
And so if we're going to use mRNA as a therapeutic, it needs our help.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
It needs protection, and it needs to be told where to go.
TED Talks Daily
The tiny balls of fat that could revolutionize medicine | Kathryn A. Whitehead
And that's where I come in.