Lester Holt

Med school was a certainty.

Autumn announced she was heading to Boston.

Her mother worried the city's crime rate was too high.

In medical school, Autumn developed a romantic thing for a research colleague and he for her.

Robert Ferranti, Bob to his friends, held a Ph.D.

in neuroscience and was hunting for cures to devastating brain illnesses like Lou Gehrig's and Huntington's diseases.

He was also more than 20 years her senior, divorced with two grown kids.

But two days before graduation from med school, a determined Autumn, wasting no time, was walking down the aisle with her much older bridegroom.

And what was your impression of him, Sharon?

Egghead?

Nerdy?

The couple made a home just outside Boston.

In a few years, a baby girl arrived into their hectic lives.

Autumn took it in stride.

The new mother was becoming a sought-after specialist in neurological ailments in women.

Because of her expertise, she was interviewed for an educational video distributed by the Discovery Channel.

But Autumn was growing frustrated with Boston, and professionally, she felt as though she'd crested there.

That's when Pittsburgh loomed into view.

In 2011, the University of Pittsburgh and its renowned Sister Medical Center offered an ideal career move.

For Bob, a new research lab.