Louisa Nicola

And sadly, we're going through an epidemic of sleep deprivation, which is classified as six hours or less. Now, I live in New York. You probably look around you. Most people are sleeping around six hours or less. That's just due to the busy city life. But during sleep, we go through different stages. And the most important stages are deep, slow-wave sleep, which is your stage three sleep.

Then we go into REM sleep, and that's stage four. And both serve very, very, very important factors for the brain. Because during deep, slow-wave sleep, you can see this on an MRI and an fMRI, right, a functional imaging machine. Your brain, we have different types of cells. You've got glial cells, which are immunity cells for the brain. We've got neurons. We've got many different other cells.

Then we go into REM sleep, and that's stage four. And both serve very, very, very important factors for the brain. Because during deep, slow-wave sleep, you can see this on an MRI and an fMRI, right, a functional imaging machine. Your brain, we have different types of cells. You've got glial cells, which are immunity cells for the brain. We've got neurons. We've got many different other cells.

Then we go into REM sleep, and that's stage four. And both serve very, very, very important factors for the brain. Because during deep, slow-wave sleep, you can see this on an MRI and an fMRI, right, a functional imaging machine. Your brain, we have different types of cells. You've got glial cells, which are immunity cells for the brain. We've got neurons. We've got many different other cells.

But these glial cells, right, they come from the Greek word glue. It's because they stick and bind to neurons. And what happens during deep, slow-wave sleep is they shrink in size. And then when they shrink, There's the passageway. It allows for the passage of the cerebral spinal fluid in your brain to flush and clean out all of the debris, all of the toxins that build up throughout the day.

But these glial cells, right, they come from the Greek word glue. It's because they stick and bind to neurons. And what happens during deep, slow-wave sleep is they shrink in size. And then when they shrink, There's the passageway. It allows for the passage of the cerebral spinal fluid in your brain to flush and clean out all of the debris, all of the toxins that build up throughout the day.

But these glial cells, right, they come from the Greek word glue. It's because they stick and bind to neurons. And what happens during deep, slow-wave sleep is they shrink in size. And then when they shrink, There's the passageway. It allows for the passage of the cerebral spinal fluid in your brain to flush and clean out all of the debris, all of the toxins that build up throughout the day.

Amyloid beta. You've got another toxic protein in the brain that builds up and aggregates, that kills cells. You've got environmental toxins that build up during the day. All these toxins build up during the day, and it's just a natural process of humans. But that's why we sleep. We sleep to replenish the brain.

Amyloid beta. You've got another toxic protein in the brain that builds up and aggregates, that kills cells. You've got environmental toxins that build up during the day. All these toxins build up during the day, and it's just a natural process of humans. But that's why we sleep. We sleep to replenish the brain.

Amyloid beta. You've got another toxic protein in the brain that builds up and aggregates, that kills cells. You've got environmental toxins that build up during the day. All these toxins build up during the day, and it's just a natural process of humans. But that's why we sleep. We sleep to replenish the brain.

So if we're not getting into deep sleep, deep slow wave sleep, we're not getting the activation of the glymphatic system. So we're not able to clear out the debris. So what happens over time? It's like compound interest. We don't clean it out one night. It may not do any harm. But if we don't clean it out two, three days a week, and that compounds over the course of 10, 20, 30 years, what happens?

So if we're not getting into deep sleep, deep slow wave sleep, we're not getting the activation of the glymphatic system. So we're not able to clear out the debris. So what happens over time? It's like compound interest. We don't clean it out one night. It may not do any harm. But if we don't clean it out two, three days a week, and that compounds over the course of 10, 20, 30 years, what happens?

So if we're not getting into deep sleep, deep slow wave sleep, we're not getting the activation of the glymphatic system. So we're not able to clear out the debris. So what happens over time? It's like compound interest. We don't clean it out one night. It may not do any harm. But if we don't clean it out two, three days a week, and that compounds over the course of 10, 20, 30 years, what happens?

It's like waste products just build up. The garbage, you've got to throw out the trash. If the garbage man doesn't come and take the trash out, what happens? Piles and piles and piles. And out of nowhere, it becomes a clump. And that is then an amyloid beta compound. I would say, ball in your brain that eventually leads to neuron death.

It's like waste products just build up. The garbage, you've got to throw out the trash. If the garbage man doesn't come and take the trash out, what happens? Piles and piles and piles. And out of nowhere, it becomes a clump. And that is then an amyloid beta compound. I would say, ball in your brain that eventually leads to neuron death.

It's like waste products just build up. The garbage, you've got to throw out the trash. If the garbage man doesn't come and take the trash out, what happens? Piles and piles and piles. And out of nowhere, it becomes a clump. And that is then an amyloid beta compound. I would say, ball in your brain that eventually leads to neuron death.

Exactly. And you know, now the latest research is showing that even more important than quality and quantity is regularity of sleep, what time you go to sleep and what time you wake up, which makes sense when you understand the evolution of the brain, because your brain loves certainty. It loves regularity. It loves to know that you're doing the same thing over and over again.

Exactly. And you know, now the latest research is showing that even more important than quality and quantity is regularity of sleep, what time you go to sleep and what time you wake up, which makes sense when you understand the evolution of the brain, because your brain loves certainty. It loves regularity. It loves to know that you're doing the same thing over and over again.

Exactly. And you know, now the latest research is showing that even more important than quality and quantity is regularity of sleep, what time you go to sleep and what time you wake up, which makes sense when you understand the evolution of the brain, because your brain loves certainty. It loves regularity. It loves to know that you're doing the same thing over and over again.

So if you can be going to sleep at the same time and waking up at the same time every day, you're going to just naturally increase your deep and slow wave sleep because you're going to be waking up with the sun, going to sleep when the sun is going down, and you're going to get this natural rhythm, if you will.