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Louisa Nicola

👤 Person
618 total appearances

Appearances Over Time

Podcast Appearances

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

The biggest misconceptions that I see with Alzheimer's disease is that it is just something you get as we get older. But I have to say that dementia is not part, not a natural aging disease. We do not have to get this disease. It is completely preventable.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

Yeah, so what you end up doing, you get a pre-dementia state is called mild cognitive impairment. And we can test this. I've done several brain scans and I've picked up on mild cognitive impairment. It's a pre-dementia state. So now you've reached... healthy to pre-dementia. So if we are in that category, then it becomes, how can we slow the progression of getting Alzheimer's disease?

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

Yeah, so what you end up doing, you get a pre-dementia state is called mild cognitive impairment. And we can test this. I've done several brain scans and I've picked up on mild cognitive impairment. It's a pre-dementia state. So now you've reached... healthy to pre-dementia. So if we are in that category, then it becomes, how can we slow the progression of getting Alzheimer's disease?

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

Yeah, so what you end up doing, you get a pre-dementia state is called mild cognitive impairment. And we can test this. I've done several brain scans and I've picked up on mild cognitive impairment. It's a pre-dementia state. So now you've reached... healthy to pre-dementia. So if we are in that category, then it becomes, how can we slow the progression of getting Alzheimer's disease?

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

Rather than getting it in 10 years or 15 years, how do I eventually get it in 30 years? So these diseases start in your 30s.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

Rather than getting it in 10 years or 15 years, how do I eventually get it in 30 years? So these diseases start in your 30s.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

Rather than getting it in 10 years or 15 years, how do I eventually get it in 30 years? So these diseases start in your 30s.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

No, look, it's always a good time to start working on your brain. One thing I will tell you, if this is not going to shock people, is we've just had in the United States a new FDA-approved drug that came out on the market. This was around two weeks ago, licanumab or Lekembe. And it's a monoclonal antibody. It's done via an IV.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

No, look, it's always a good time to start working on your brain. One thing I will tell you, if this is not going to shock people, is we've just had in the United States a new FDA-approved drug that came out on the market. This was around two weeks ago, licanumab or Lekembe. And it's a monoclonal antibody. It's done via an IV.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

No, look, it's always a good time to start working on your brain. One thing I will tell you, if this is not going to shock people, is we've just had in the United States a new FDA-approved drug that came out on the market. This was around two weeks ago, licanumab or Lekembe. And it's a monoclonal antibody. It's done via an IV.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

So if you have the disease, what it does is you put the IV in and over some time, it can apparently ameliorate the amyloid beta, freeing up the brain to get back to its normal state. So many things wrong with that. First and foremost is while that may be true, in the process of it doing that, we've seen patients actually get brain bleeds and affecting the ventricles of the brain.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

So if you have the disease, what it does is you put the IV in and over some time, it can apparently ameliorate the amyloid beta, freeing up the brain to get back to its normal state. So many things wrong with that. First and foremost is while that may be true, in the process of it doing that, we've seen patients actually get brain bleeds and affecting the ventricles of the brain.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

So if you have the disease, what it does is you put the IV in and over some time, it can apparently ameliorate the amyloid beta, freeing up the brain to get back to its normal state. So many things wrong with that. First and foremost is while that may be true, in the process of it doing that, we've seen patients actually get brain bleeds and affecting the ventricles of the brain.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

So even though you may be ameliorating some of the amyloid beta, which by the way, it's a very small amount, a very small amount. In that time you've wasted, it's around $60,000 a year for that drug. You're also increasing your risk of hemorrhaging, like brain bleeds affecting the ventricles of the brain. And so I think to myself,

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

So even though you may be ameliorating some of the amyloid beta, which by the way, it's a very small amount, a very small amount. In that time you've wasted, it's around $60,000 a year for that drug. You're also increasing your risk of hemorrhaging, like brain bleeds affecting the ventricles of the brain. And so I think to myself,

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

So even though you may be ameliorating some of the amyloid beta, which by the way, it's a very small amount, a very small amount. In that time you've wasted, it's around $60,000 a year for that drug. You're also increasing your risk of hemorrhaging, like brain bleeds affecting the ventricles of the brain. And so I think to myself,

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

No matter what, you do not want to get the disease because it's not going to be good for somebody who you're living with. It's not going to be good for your economic status because it's around $60,000 a year. And at the end of the day, it's having maybe a 0.1% change in your brain.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

No matter what, you do not want to get the disease because it's not going to be good for somebody who you're living with. It's not going to be good for your economic status because it's around $60,000 a year. And at the end of the day, it's having maybe a 0.1% change in your brain.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

No matter what, you do not want to get the disease because it's not going to be good for somebody who you're living with. It's not going to be good for your economic status because it's around $60,000 a year. And at the end of the day, it's having maybe a 0.1% change in your brain.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

Yeah. Correct, yeah, aducanumab, yes, from Biogen, which was actually retracted as well.