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Louisa Nicola

👤 Person
618 total appearances

Appearances Over Time

Podcast Appearances

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

Another one called irisin, which was named after the Greek god of Iris. It's a messenger molecule. So when that gets excreted from the muscle belly and goes into the brain, it actually tells BDNF to express itself even more. We've got cathepsin B, myostatin. We've got IL-6. interleukin-6, which is originally a pro-inflammatory cytokine.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

But when it's released from the muscle specifically, it becomes anti-inflammatory. So there we go. We're going to be down-regulating inflammation from resistance training. So you can build a better brain through resistance training alone. We're now even seeing maximal aerobic exercise and resistance training having an effect on circulating blood

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

But when it's released from the muscle specifically, it becomes anti-inflammatory. So there we go. We're going to be down-regulating inflammation from resistance training. So you can build a better brain through resistance training alone. We're now even seeing maximal aerobic exercise and resistance training having an effect on circulating blood

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

But when it's released from the muscle specifically, it becomes anti-inflammatory. So there we go. We're going to be down-regulating inflammation from resistance training. So you can build a better brain through resistance training alone. We're now even seeing maximal aerobic exercise and resistance training having an effect on circulating blood

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

circulating tumor cells so when a tumor is formed for example this is a really great study in cell press it was to do with prostate cancer and the inhibition of prostate cancer via these myokines but what happens is let's just say you form a mass if you will at stage one

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

circulating tumor cells so when a tumor is formed for example this is a really great study in cell press it was to do with prostate cancer and the inhibition of prostate cancer via these myokines but what happens is let's just say you form a mass if you will at stage one

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

circulating tumor cells so when a tumor is formed for example this is a really great study in cell press it was to do with prostate cancer and the inhibition of prostate cancer via these myokines but what happens is let's just say you form a mass if you will at stage one

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

That tends to break and I'm not an oncologist, but I'm reading the research that tends to break off and you get these circulating tumor cells and they end up going and aggregating and forming another tumor, which ends up becoming metastases. We now have evidence that the sheer force and shunting of blood flow through aerobic and maximal exercise can ameliorate these circulating tumor cells.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

That tends to break and I'm not an oncologist, but I'm reading the research that tends to break off and you get these circulating tumor cells and they end up going and aggregating and forming another tumor, which ends up becoming metastases. We now have evidence that the sheer force and shunting of blood flow through aerobic and maximal exercise can ameliorate these circulating tumor cells.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

That tends to break and I'm not an oncologist, but I'm reading the research that tends to break off and you get these circulating tumor cells and they end up going and aggregating and forming another tumor, which ends up becoming metastases. We now have evidence that the sheer force and shunting of blood flow through aerobic and maximal exercise can ameliorate these circulating tumor cells.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

And not just that, these myokines can inhibit the growth of these prostate cancer cells. So you're not just having an effect on the brain. We're now seeing exercise and cancer. this crosstalk between the two. So we're just probably at the early stages of that. But resistance training should be part of your hygiene as well, your daily hygiene.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

And not just that, these myokines can inhibit the growth of these prostate cancer cells. So you're not just having an effect on the brain. We're now seeing exercise and cancer. this crosstalk between the two. So we're just probably at the early stages of that. But resistance training should be part of your hygiene as well, your daily hygiene.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

And not just that, these myokines can inhibit the growth of these prostate cancer cells. So you're not just having an effect on the brain. We're now seeing exercise and cancer. this crosstalk between the two. So we're just probably at the early stages of that. But resistance training should be part of your hygiene as well, your daily hygiene.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

You want to be shooting for three to four days a week of resistance training, but here's the caveat. You have to be going hard. We know that more is better when it comes to how much, how many myokines are released. So when I say more, meaning that you really want to stress the muscles of, you really want to stress your biceps, for example.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

You want to be shooting for three to four days a week of resistance training, but here's the caveat. You have to be going hard. We know that more is better when it comes to how much, how many myokines are released. So when I say more, meaning that you really want to stress the muscles of, you really want to stress your biceps, for example.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

You want to be shooting for three to four days a week of resistance training, but here's the caveat. You have to be going hard. We know that more is better when it comes to how much, how many myokines are released. So when I say more, meaning that you really want to stress the muscles of, you really want to stress your biceps, for example.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

So you want to be lifting at around 75 to 80% of your one repetition max and A lot of people may be saying, well, what is that? Basically, you want to be lifting to the point where you get to rep six. It's really difficult, like you're shaking. So you really want to be working hard out. You want to be doing three to four days a week of resistance training alone.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

So you want to be lifting at around 75 to 80% of your one repetition max and A lot of people may be saying, well, what is that? Basically, you want to be lifting to the point where you get to rep six. It's really difficult, like you're shaking. So you really want to be working hard out. You want to be doing three to four days a week of resistance training alone.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

So you want to be lifting at around 75 to 80% of your one repetition max and A lot of people may be saying, well, what is that? Basically, you want to be lifting to the point where you get to rep six. It's really difficult, like you're shaking. So you really want to be working hard out. You want to be doing three to four days a week of resistance training alone.

Dhru Purohit Show
Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

You want to be doing three hours a week at minimum of aerobic zone two training.