The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
And it carried a poison with it.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
They're called antibody drug conjugates.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
So you attach a nasty chemical to an antibody that targets this thing, B7H4, and the chemical kills the cell.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
There's been a few ideas around this already in the past.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
This is probably the first example of it really working.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
I mean, you see, that kind of response would predict a huge effect down the line, then, is the idea.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
And what was interesting about it, they got it from China.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
Increasingly, the Chinese are discovering new medicines.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
This wasn't the case in the past.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
And GSK saw this Chinese company, looked at the drug, looked at their data, bought the drug in from China, and now we're seeing this big effect on ovarian.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
And GSK themselves are saying this will be a blockbuster.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
Because that ovarian is very common.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
And again, not much is about to treat it.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
If you can imagine a drug that gets through, they're predicting billions in sales.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
How much of this is to do with AI being employed, or is this just old-fashioned, good, solid research?
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
I think these are good-fashioned, old-fashioned stuff at the moment, in a way.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
They will use AI path on the trials, remember, to assess the patients and see who's responding.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
And I suspect with GSK, they found that 62% response rate through AI probably is part of it.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
Okay, so it seems like everything's gathering apace.
The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer
I mean, I see stuff online every day about development and Parkinson's disease and all of that.