Lynne Peeples
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Podcast Appearances
And scientists are finding that night owls and patients with weak circadian rhythms tend to actually respond poorly to, for example, lithium. And he's also finding, or he's thinking one reason for that is that lithium lengthens and strengthens circadian rhythms. So for those that respond well, that's what's happening.
And scientists are finding that night owls and patients with weak circadian rhythms tend to actually respond poorly to, for example, lithium. And he's also finding, or he's thinking one reason for that is that lithium lengthens and strengthens circadian rhythms. So for those that respond well, that's what's happening.
And that could potentially explain the benefit for lithium to some patients and the fact that it really doesn't work for other patients. And so this kind of line of research, thinking about this for various treatments, as well as the idea that
And that could potentially explain the benefit for lithium to some patients and the fact that it really doesn't work for other patients. And so this kind of line of research, thinking about this for various treatments, as well as the idea that
And that could potentially explain the benefit for lithium to some patients and the fact that it really doesn't work for other patients. And so this kind of line of research, thinking about this for various treatments, as well as the idea that
Focusing directly on helping a patient's circadian rhythms, again, through these techniques we're talking about, you know, getting more light during the day, darkness at night, eating patterns and such, that could potentially be a strong treatment itself. And then the idea comes up that, you know, this vicious spiral that happens with a lot of mental health disorders where...
Focusing directly on helping a patient's circadian rhythms, again, through these techniques we're talking about, you know, getting more light during the day, darkness at night, eating patterns and such, that could potentially be a strong treatment itself. And then the idea comes up that, you know, this vicious spiral that happens with a lot of mental health disorders where...
Focusing directly on helping a patient's circadian rhythms, again, through these techniques we're talking about, you know, getting more light during the day, darkness at night, eating patterns and such, that could potentially be a strong treatment itself. And then the idea comes up that, you know, this vicious spiral that happens with a lot of mental health disorders where...
Somebody is depressed, for example, and they're indoors during the day. Well, on average, we all spend a majority of our days indoors, at least 90%. But being indoors and missing that morning light then sets them up to more likely stay awake later at night. And then that's going to set them up to sleep in the next day. And overall, that's going to weaken their rhythms.
Somebody is depressed, for example, and they're indoors during the day. Well, on average, we all spend a majority of our days indoors, at least 90%. But being indoors and missing that morning light then sets them up to more likely stay awake later at night. And then that's going to set them up to sleep in the next day. And overall, that's going to weaken their rhythms.
Somebody is depressed, for example, and they're indoors during the day. Well, on average, we all spend a majority of our days indoors, at least 90%. But being indoors and missing that morning light then sets them up to more likely stay awake later at night. And then that's going to set them up to sleep in the next day. And overall, that's going to weaken their rhythms.
And if there's a link between that and the disorder itself, it creates the snowball effect that some of the science is pointing to potentially a way out.
And if there's a link between that and the disorder itself, it creates the snowball effect that some of the science is pointing to potentially a way out.
And if there's a link between that and the disorder itself, it creates the snowball effect that some of the science is pointing to potentially a way out.
Right. So there is mounting data that is finding correlations between circadian disruption as well as exposure to light at night and cancer. So the jury is still out on really, you know, directly linking the two. But the science is pretty clear that as we disrupt our rhythms and we disrupt our immune system and, again, our ability to metabolize food at the right times of day and all these things,
Right. So there is mounting data that is finding correlations between circadian disruption as well as exposure to light at night and cancer. So the jury is still out on really, you know, directly linking the two. But the science is pretty clear that as we disrupt our rhythms and we disrupt our immune system and, again, our ability to metabolize food at the right times of day and all these things,
Right. So there is mounting data that is finding correlations between circadian disruption as well as exposure to light at night and cancer. So the jury is still out on really, you know, directly linking the two. But the science is pretty clear that as we disrupt our rhythms and we disrupt our immune system and, again, our ability to metabolize food at the right times of day and all these things,
It's not a shock to scientists that there could be ramifications for how that could propel the development of cancer and heart disease, other cardiometabolic disorders, and then in the long term, potentially dementia. The hypothesis at this point is it's probably bidirectional when we think about that, because we know that
It's not a shock to scientists that there could be ramifications for how that could propel the development of cancer and heart disease, other cardiometabolic disorders, and then in the long term, potentially dementia. The hypothesis at this point is it's probably bidirectional when we think about that, because we know that
It's not a shock to scientists that there could be ramifications for how that could propel the development of cancer and heart disease, other cardiometabolic disorders, and then in the long term, potentially dementia. The hypothesis at this point is it's probably bidirectional when we think about that, because we know that