Marc Andreessen

For example, embryos from stem cells, couples that can't, you know, you probably know a lot of people like this, people who get to a point, either they had a fertility problem when they were young or they get to an age where they have fertility issues, but they want more kids. And then they're forced into very difficult choices having to do with IVF or donors of different kinds.

For example, embryos from stem cells, couples that can't, you know, you probably know a lot of people like this, people who get to a point, either they had a fertility problem when they were young or they get to an age where they have fertility issues, but they want more kids. And then they're forced into very difficult choices having to do with IVF or donors of different kinds.

It looks like we're going to be able to have embryos from stem cells. And so you can have children that are actual biological children much later in life. External gestation is a while away still, but at some point that might be a big deal. People talk about the birth rate a lot.

It looks like we're going to be able to have embryos from stem cells. And so you can have children that are actual biological children much later in life. External gestation is a while away still, but at some point that might be a big deal. People talk about the birth rate a lot.

Well, if you could continue to have kids into your 60s, and if you could have a dozen kids because you could have external gestation, would more people choose to do that? And maybe yes. So that would be one. Another might be, say, genetic optimization. So one of the endlessly spicy topics is intelligence augmentation. There's CRISPR. We now have gene editing technology.

Well, if you could continue to have kids into your 60s, and if you could have a dozen kids because you could have external gestation, would more people choose to do that? And maybe yes. So that would be one. Another might be, say, genetic optimization. So one of the endlessly spicy topics is intelligence augmentation. There's CRISPR. We now have gene editing technology.

So in theory, you can go in and do genetic reprogramming of people, especially at the early stages. And then the scientists are figuring out the hundreds of genes that correspond to IQ. And so should you have the ability to boost IQ? That has all kinds of downstream questions. So probably it's in that vanguard, those kind of vanguard movements.

So in theory, you can go in and do genetic reprogramming of people, especially at the early stages. And then the scientists are figuring out the hundreds of genes that correspond to IQ. And so should you have the ability to boost IQ? That has all kinds of downstream questions. So probably it's in that vanguard, those kind of vanguard movements.

The inflammatory version of this was the guy in China who made the babies who were immune to AIDS. So there was the Chinese guy who did a homebrew CRISPR thing. And he created two embryos that are now, I think, living children, as far as I know, that use CRISPR to splice in genes that make them immune to HIV.

The inflammatory version of this was the guy in China who made the babies who were immune to AIDS. So there was the Chinese guy who did a homebrew CRISPR thing. And he created two embryos that are now, I think, living children, as far as I know, that use CRISPR to splice in genes that make them immune to HIV.

And it became this dramatic firestorm of controversy because CRISPR is not developed well enough yet to do that in a predictable way. And so there were accusations that he was really going to be damaging these kids. And this global health ethics world came up in one and basically was horrified by what he did.

And it became this dramatic firestorm of controversy because CRISPR is not developed well enough yet to do that in a predictable way. And so there were accusations that he was really going to be damaging these kids. And this global health ethics world came up in one and basically was horrified by what he did.

And then George Church, who's probably the leading biology researcher in the West right now, actually gave a counterargument. And he's like, no, people need to do this. We need to actually try these things. I'm not even taking a position on this. I'm not even saying these things are good or bad or should be allowed or should be banned or whatever.

And then George Church, who's probably the leading biology researcher in the West right now, actually gave a counterargument. And he's like, no, people need to do this. We need to actually try these things. I'm not even taking a position on this. I'm not even saying these things are good or bad or should be allowed or should be banned or whatever.

Everything I just described is becoming possible. And they have these just incredible implications on everything from health to society, which will play out for hundreds of years to come. And so I think more and more people are probably going to realize that there's a lot more to discuss on those fronts than we've been doing.

Everything I just described is becoming possible. And they have these just incredible implications on everything from health to society, which will play out for hundreds of years to come. And so I think more and more people are probably going to realize that there's a lot more to discuss on those fronts than we've been doing.

Yeah, so American Dynamism covers a lot of territory and we do a lot in there. We're doing more in energy. We have our first nuclear investment. We're doing education, other fields. And so there's a lot in there, this theme of upgrading America. For me, the most fascinating thing is the change in military affairs.

Yeah, so American Dynamism covers a lot of territory and we do a lot in there. We're doing more in energy. We have our first nuclear investment. We're doing education, other fields. And so there's a lot in there, this theme of upgrading America. For me, the most fascinating thing is the change in military affairs.

So the change in the nature of war and defense that's coming from the rise of technologies like AI and autonomy. Highlight a couple of things there. So one is it's actually happening. And in particular, the tragedy of the Ukraine battlefield is also just turns out to be a living laboratory for extremely rapid evolution of military technology.

So the change in the nature of war and defense that's coming from the rise of technologies like AI and autonomy. Highlight a couple of things there. So one is it's actually happening. And in particular, the tragedy of the Ukraine battlefield is also just turns out to be a living laboratory for extremely rapid evolution of military technology.