Marty Makary

speaker

939 appearances 6 recordings 5 series first heard Jan 2026 last heard 13 May

Marty Makary’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 6 in all, peaking in Jan 2026 with 4.

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Freakonomics Radio · 659. Can Marty Makary Fix the F.D.A.? · 16 Jan 2026 podcast

And which kids does it not help?

We do know from the experience of very busy, respected clinicians who treat a lot of kids with severe autism that maybe 20% of the kids have a marked improvement with leucovorin.

Maybe another 30% to 40% may have some improvement.

And the rest of the kids, they just don't see.

They can't tell.

So identifying who those are who can benefit the most is a part of the ongoing research.

I think the Tylenol story really got legs when Harvard and Mount Sinai published, about a month prior, a review article looking at the body of evidence of studies for and against acetaminophen.

It was 27 studies showing an association between prenatal acetaminophen and autism, and about 13 to 14 studies that went the other way.

So the research was mixed.

The dean of the Harvard School of Public Health

weighed in and said he feels strongly that there is an association.

And so I think that was the basis for saying we're going to make this information available to individuals.

You know, when you open up a prescription medication or over-the-counter medication, there's a paper folded like 15 times, and you open it up and it's got a million words on it that nobody reads.

Part of that is a little section about what we know about in pregnancy.

So we felt that it was reasonable, given the strong views of the dean of the Harvard School of Public Health.

Well, I think the media coverage on this has been very incomplete because they'll pull a clip of a phrase that he said, but they leave out that he has said repeatedly in the exact same talk that there are exceptions, that sometimes a woman needs to take it, and that ultimately it's between an individual and their doctor.

Those points were left out entirely in our politically charged media landscape.

I think we saw it during COVID.

You had, for example, the American Academy of Pediatrics insist in the first year of COVID that schools should be open in the fall of 2020.

And that was their message until President Trump said the same thing.

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