Max Lugavere
👤 SpeakerAppearances Over Time
Podcast Appearances
It's not a reversible condition.
We don't have the data to say that, but you can slow its progression.
I think the data is pretty clear on this, that with regular vigorous exercise by optimizing sleep and by optimizing around a whole foods nutrient rich, antioxidant rich diet, I think that that can really go a long way.
Slowing the course, I think is the best that we can hope for.
And that is a big win if you can do that.
I think that's crucially important.
And then when it comes to other interventions, there are precious few tools in the toolkit when it comes to effectively treating Alzheimer's disease.
Alzheimer's drug trials have a 99.6% fail rate.
It's dismal.
There is this growing signal that creatine might help.
And I'm not yet going to make the recommendation that people should go out and start giving their loved ones heaps of creatine.
But there was a pilot study that came out a couple of months ago.
It didn't have a placebo group and it used a very high dose of creatine.
But nonetheless, it found that this dose was safe and effective.
for improving cognitive function in patients with Alzheimer's disease.
There's also a signal.
We need more research on this.
It's certainly not a cure, but for years, there's been this body of literature suggesting that ketogenic diets might play a potential role in keeping quality of life
Yeah, avoiding processed carbs and also importantly, giving the brain sort of a backdoor energetic substrate to create energy from, which are ketones.
So whether it's, you know, a ketogenic diet, which admittedly is a really hard diet to adhere to, but they have ketogenic products on the market now.