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Max Lugavere

👤 Speaker
8803 total appearances

Appearances Over Time

Podcast Appearances

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

It's not a reversible condition.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

We don't have the data to say that, but you can slow its progression.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

I think the data is pretty clear on this, that with regular vigorous exercise by optimizing sleep and by optimizing around a whole foods nutrient rich, antioxidant rich diet, I think that that can really go a long way.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

Slowing the course, I think is the best that we can hope for.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

And that is a big win if you can do that.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

I think that's crucially important.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

And then when it comes to other interventions, there are precious few tools in the toolkit when it comes to effectively treating Alzheimer's disease.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

Alzheimer's drug trials have a 99.6% fail rate.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

It's dismal.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

There is this growing signal that creatine might help.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

And I'm not yet going to make the recommendation that people should go out and start giving their loved ones heaps of creatine.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

But there was a pilot study that came out a couple of months ago.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

It didn't have a placebo group and it used a very high dose of creatine.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

But nonetheless, it found that this dose was safe and effective.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

for improving cognitive function in patients with Alzheimer's disease.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

There's also a signal.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

We need more research on this.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

It's certainly not a cure, but for years, there's been this body of literature suggesting that ketogenic diets might play a potential role in keeping quality of life

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

Yeah, avoiding processed carbs and also importantly, giving the brain sort of a backdoor energetic substrate to create energy from, which are ketones.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

So whether it's, you know, a ketogenic diet, which admittedly is a really hard diet to adhere to, but they have ketogenic products on the market now.